Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2799878 | 0.79 | APP (0.44) | APPMAPTLMNAALDH1A1HPGD | |
| SCHEMBL18105076 | 0.75 | APP (0.55) | APPMAPTLMNAALDH1A1HPGD | |
| SCHEMBL19062293 | 0.75 | APP (0.55) | APPMAPTLMNAALDH1A1HPGD | |
| SCHEMBL1657799 | 0.71 | APP (0.50) | APPMAPTLMNAALDH1A1HPGD | |
| SCHEMBL1657802 | 0.71 | APP (0.50) | APPMAPTLMNAALDH1A1HPGD | |
| SCHEMBL24081316 | 0.71 | APP (0.50) | APPMAPTLMNAALDH1A1HPGD | |
| SCHEMBL9389594 | 0.71 | APP (0.50) | APPMAPTLMNAALDH1A1HPGD | |
| SCHEMBL28900542 | 0.71 | APP (0.50) | APPMAPTLMNAALDH1A1HPGD | |
| SCHEMBL2311776 | 0.71 | APP (0.50) | APPMAPTLMNAALDH1A1HPGD | |
| SCHEMBL9119338 | 0.71 | APP (0.50) | APPMAPTLMNAALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59164741-A | — | — | None | — | — | JP | disclosed |
| CN-114409501-B | Method for preparing propargyl alcohol compound by taking pinacol borane as hydrogen source | 云南民族大学 | 2024-05-10 | — | — | CN | disclosed |
| CN-114409501-A | Method for preparing propargyl alcohol compound by taking pinacol borane as hydrogen source | 云南民族大学 | 2022-04-29 | — | — | CN | disclosed |
| EP-1476423-A4 | ARYLSULFONAMIDOBENZYLIC COMPOUNDS | TULARIK INC (US) | 2005-12-14 | — | — | EP | disclosed |
| EP-1476423-A2 | ARYLSULFONAMIDOBENZYLIC COMPOUNDS | Tularik Inc. (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003063576-A2 | ARYLSULFONAMIDOBENZYLIC COMPOUNDS | TULARIK INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| US-4532020-A | Reacting alkyne with fluorine-containing aldehyde in presence of catalyst under ultrasonic irradiation | DAIKIN KOGYO CO., LTD. (JP) | 1985-07-30 | — | — | US | disclosed |
| EP-0118890-A1 | Process for preparing a beta-(fluoroalkyl or fluoroalkenyl)-beta-hydroxyalkyne and an alpha-(fluoroalkyl or fluoroalkenyl)-allyl alcohol thereof | Daikin Kogyo Co., Ltd. (JP) | 1984-09-19 | — | — | EP | disclosed |
| JP-S59164741-A | PREPARATION OF BETA-(FLUOROALKYL OR ALKENYL)-BETA- HYDROXYALKYNE | DAIKIN IND LTD | 1984-09-17 | — | — | JP | disclosed |