Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062293 | 0.80 | APP (0.55) | APPHSD17B2MAPTLMNAKDM4E | |
| SCHEMBL18105076 | 0.80 | APP (0.55) | APPHSD17B2MAPTLMNAKDM4E | |
| SCHEMBL1657802 | 0.76 | APP (0.50) | APPHSD17B2MAPTLMNAKDM4E | |
| SCHEMBL9389594 | 0.76 | APP (0.50) | APPHSD17B2MAPTLMNAKDM4E | |
| SCHEMBL1657799 | 0.76 | APP (0.50) | APPHSD17B2MAPTLMNAKDM4E | |
| SCHEMBL24081316 | 0.76 | APP (0.50) | APPHSD17B2MAPTLMNAKDM4E | |
| SCHEMBL2311776 | 0.76 | APP (0.50) | APPHSD17B2MAPTLMNAKDM4E | |
| SCHEMBL28900542 | 0.76 | APP (0.50) | APPHSD17B2MAPTLMNAKDM4E | |
| SCHEMBL2569114 | 0.76 | LMNA (0.48) | APPLMNAKDM4ECYP1A2CYP3A4 | |
| SCHEMBL2801832 | 0.74 | TSHR (0.52) | APPMAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446203-A | Synthesis of haloenones and aryl or alkyl substituted enones or alkenes | NEW YORK UNIVERSITY (US) | 1995-08-29 | — | — | US | disclosed |