Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989290 | 0.83 | CA1 (0.44) | KMT2ASTSEPAS1KDM4EALDH1A1 | |
| SCHEMBL31195498 | 0.83 | CA1 (0.44) | KMT2ASTSEPAS1KDM4EALDH1A1 | |
| SCHEMBL13239263 | 0.81 | EPAS1 (0.41) | EPAS1ALDH1A1POLBLMNA | |
| SCHEMBL31195545 | 0.81 | MRGPRX4 (0.40) | STSEPAS1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6511762 | 0.81 | DRD2 (0.39) | KMT2AMEN1KDM4EALDH1A1LMNA | |
| SCHEMBL4769962 | 0.81 | PTGDR2 (0.42) | EPAS1SMN1; SMN2 | |
| SCHEMBL29365046 | 0.80 | CA1 (0.50) | KMT2ASTSKDM4EALDH1A1NPSR1 | |
| SCHEMBL31204476 | 0.80 | TSHR (0.46) | STSEPAS1KDM4EALDH1A1NPSR1 | |
| SCHEMBL1772862 | 0.80 | CA1 (0.50) | KMT2ASTSKDM4EALDH1A1NPSR1 | |
| SCHEMBL6139651 | 0.80 | TSHR (0.41) | RAB9AKMT2AMEN1EPAS1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196403-B1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | SANOFI AVENTIS (FR) | 2005-11-09 | — | — | EP | disclosed |
| US-6908914-B1 | Antipsychotic cyclic N-aralkylamines | SANOFI-SYNTHELABO (FR) | 2005-06-21 | — | — | US | disclosed |
| EP-1196403-A1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | Sanofi-Aventis (FR) | 2002-04-17 | — | — | EP | disclosed |
| WO-2001002380-A1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | SANOFI-SYNTHELABO (FR) | 2001-01-11 | — | — | WO | disclosed |