SCHEMBL6139852

SCHEMBL6139852

COc1ccc(N(c2ccc(OC)cc2)c2ccc(-c3ccc(C=C(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.61
KDM4E B2RXH2 1/20 0.61
ALDH1A1 P00352 1/20 0.61
HPGD P15428 1/20 0.61
CYP2D6 P10635 1/20 0.46
TRPM8 Q7Z2W7 3/20 0.45
BCHE P06276 1/20 0.44
CYP3A4 P08684 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
TRPA1 O75762 1/20 0.44
PTGS2 P35354 1/20 0.43
ALOX5 P09917 1/20 0.43
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41
CYP19A1 P11511 1/20 0.41
CYP11B2 P19099 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140125 1.00 MAPT (0.61) MAPTKDM4EALDH1A1HPGDCYP2D6
SCHEMBL2210195 0.96 MAPT (0.67) MAPTKDM4EALDH1A1HPGDCYP2D6
SCHEMBL6140217 0.96 MAPT (0.67) MAPTKDM4EALDH1A1HPGDCYP2D6
SCHEMBL12009444 0.94 KDM4E (0.65) MAPTKDM4EALDH1A1HPGDCYP2D6
SCHEMBL6033516 0.94 KDM4E (0.65) MAPTKDM4EALDH1A1HPGDCYP2D6
SCHEMBL8449065 0.91 KDM4E (0.70) MAPTKDM4EALDH1A1HPGDCYP2D6
SCHEMBL7159491 0.91 KDM4E (0.70) MAPTKDM4EALDH1A1HPGDCYP2D6
SCHEMBL12533946 0.90 MAPT (0.59) MAPTKDM4EALDH1A1HPGDCYP2D6
SCHEMBL13026509 0.89 MAPT (0.62) MAPTKDM4EALDH1A1HPGDCYP2D6
SCHEMBL2605606 0.89 MAPT (0.62) MAPTKDM4EALDH1A1HPGDCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050031902-A1 Organic EL device, method of manufacturing the same, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2005-02-10 US disclosed
EP-1505647-A2 Organic EL device, method of manufacturing the same and electronic apparatus Seiko Epson Corporation (JP) 2005-02-09 EP disclosed