Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.36 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28223088 | 1.00 | SIGMAR1 (0.50) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL611936 | 1.00 | SIGMAR1 (0.50) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL614707 | 1.00 | SIGMAR1 (0.50) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL10712750 | 1.00 | SIGMAR1 (0.50) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL614861 | 1.00 | SIGMAR1 (0.50) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL614494 | 1.00 | SIGMAR1 (0.50) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL615431 | 1.00 | SIGMAR1 (0.50) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL28222365 | 1.00 | SIGMAR1 (0.50) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL441443 | 0.97 | SIGMAR1 (0.52) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 | |
| SCHEMBL10893528 | 0.95 | PLA2G1B (0.48) | SIGMAR1PLA2G1BPLA2G2ALMNACACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421874-B1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2015-09-30 | — | — | EP | claimed |
| US-8979996-B2 | Composition containing quaternary amino-functional organosilicon compunds and production and use thereof | EVONIK DEGUSSA GMBH (DE) | 2015-03-17 | — | — | US | claimed |
| US-20140208981-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2014-07-31 | — | — | US | claimed |
| US-8728225-B2 | Composition containing quaternary amino-functional organosilicon compounds and production and use thereof | EVONIK DEGUSSA GMBH (DE) | 2014-05-20 | — | — | US | claimed |
| US-20120037040-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2012-02-16 | — | — | US | claimed |
| US-7129366-B2 | Group of a novel anti-cancer compounds with specific structure | YANG'S BIOCHEM CO. LTD. (US) | 2006-10-31 | — | — | US | claimed |
| EP-1463707-A4 | A GROUP OF NOVEL ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE | YANG ZHENHUA (US) | 2006-02-01 | — | — | EP | claimed |
| US-20040204599-A1 | Group of novel anti-cancer compounds with specific structure | YANG'S BIOCHEM CO. LTD. | 2004-10-14 | — | — | US | claimed |
| EP-1463707-A2 | A GROUP OF NOVEL ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE | Yang, Zhenhua (US) | 2004-10-06 | — | — | EP | claimed |
| WO-2003014296-A2 | A GROUP OF NOVEL ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE | YANG ZHENHUA (US) | 2003-02-20 | — | — | WO | claimed |
| EP-2421874-B1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2015-09-30 | — | — | EP | disclosed |
| US-8979996-B2 | Composition containing quaternary amino-functional organosilicon compunds and production and use thereof | EVONIK DEGUSSA GMBH (DE) | 2015-03-17 | — | — | US | disclosed |
| US-20140208981-A1 | COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF | EVONIK DEGUSSA GMBH (DE) | 2014-07-31 | — | — | US | disclosed |
| US-8747541-B2 | Dispersion containing silica particles surface-modified with quaternary, aminofunctional organosilicon compounds | EVONIK DEGUSSA GMBH (DE) | 2014-06-10 | — | — | US | disclosed |
| US-8728225-B2 | Composition containing quaternary amino-functional organosilicon compounds and production and use thereof | EVONIK DEGUSSA GMBH (DE) | 2014-05-20 | — | — | US | disclosed |
| US-7129366-B2 | Group of a novel anti-cancer compounds with specific structure | YANG'S BIOCHEM CO. LTD. (US) | 2006-10-31 | — | — | US | disclosed |
| EP-1463707-A4 | A GROUP OF NOVEL ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE | YANG ZHENHUA (US) | 2006-02-01 | — | — | EP | disclosed |
| US-20040204599-A1 | Group of novel anti-cancer compounds with specific structure | YANG'S BIOCHEM CO. LTD. | 2004-10-14 | — | — | US | disclosed |
| EP-1463707-A2 | A GROUP OF NOVEL ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE | Yang, Zhenhua (US) | 2004-10-06 | — | — | EP | disclosed |
| WO-2003014296-A2 | A GROUP OF NOVEL ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE | YANG ZHENHUA (US) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040204599-A1 | Group of novel anti-cancer compounds with specific structure | FASN, NFKBIA, NFATC1 | SIGMAR1 912/4885PLA2G1B 965/4885PLA2G2A 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.