SCHEMBL6140608

SCHEMBL6140608

CCCCC=CC=CCN1C(=O)[C@H](Cc2ccc(-c3cc(OC)c(OC)c(OC)c3)cc2)N(C)C(=O)[C@@H]1C

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FSHR P23945 20/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140780 0.92 FSHR (0.77) FSHR
SCHEMBL6140748 0.91 FSHR (0.78) FSHR
SCHEMBL6141102 0.89 FSHR (0.72) FSHR
SCHEMBL6140271 0.89 FSHR (0.66) FSHR
SCHEMBL6141134 0.84 FSHR (1.00) FSHR
SCHEMBL7189124 0.84 FSHR (1.00) FSHR
SCHEMBL7200544 0.84 FSHR (1.00) FSHR
SCHEMBL6140399 0.84 FSHR (1.00) FSHR
SCHEMBL6140785 0.84 FSHR (1.00) FSHR
SCHEMBL6140715 0.84 FSHR (1.00) FSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6900213-B2 Bisaryl derivatives having FSH modulatory activity PHARMACOPEIA DRUG DISCOVERY, INC. (US) 2005-05-31 US disclosed
EP-1351941-B1 BISARYL DERIVATIVES HAVING FSH RECEPTOR MODULATORY ACTIVITY PHARMACOPEIA INC (US) 2004-09-29 EP disclosed
US-20040152703-A1 Bisaryl derivatives having FSH modulatory activity PHARMACOPEIA, LLC 2004-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152703-A1 Bisaryl derivatives having FSH modulatory activity FSHR, GNRHR, LHCGR FSHR 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.