Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.41 |
| ▸ | YES1 | P07947 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
| ▸ | CIT | O14578 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613798 | 0.91 | ESR1 (0.45) | SRCLRRK2PDGFRBYES1PLK1 | |
| SCHEMBL614557 | 0.85 | SRC (0.63) | SRCPDGFRBYES1JAK2ESR1 | |
| SCHEMBL613791 | 0.84 | SRC (0.42) | SRCLRRK2JAK2SYKTTK | |
| SCHEMBL612666 | 0.83 | SRC (0.55) | SRCPDGFRBYES1JAK2EGFR | |
| SCHEMBL612376 | 0.81 | SRC (0.46) | SRCLRRK2PDGFRBYES1JAK2 | |
| SCHEMBL613388 | 0.80 | LRRK2 (0.47) | SRCLRRK2PDGFRBJAK2EGFR | |
| SCHEMBL613040 | 0.78 | LRRK2 (0.52) | SRCLRRK2PDGFRBYES1JAK2 | |
| SCHEMBL41009 | 0.78 | LRRK2 (0.47) | SRCLRRK2PDGFRBJAK2TTK | |
| SCHEMBL615192 | 0.77 | LRRK2 (0.48) | SRCLRRK2PDGFRBYES1JAK2 | |
| SCHEMBL41122 | 0.76 | SRC (0.53) | SRCLRRK2PDGFRBJAK2TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041195-A1 | Heterocyclic compounds | FOVEA PHARMACEUTICALS | 2012-02-16 | — | — | US | claimed |
| US-20120041195-A1 | Heterocyclic compounds | FOVEA PHARMACEUTICALS | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041195-A1 | Heterocyclic compounds | MAP3K1, MAP3K5, MAP3K2 | SRC 1204/4885LRRK2 391/4885AGER 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.