Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738919 | 1.00 | PRCP (0.60) | PRCPGAAMAPTSMN1; SMN2MEN1 | |
| Tert-Butyl Formate SCHEMBL27626763 | 0.83 | PRCP (0.44) | PRCPGAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL2707254 | 0.80 | PRCP (0.47) | PRCPGAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL29330477 | 0.80 | PRCP (0.47) | PRCPGAAMAPTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL29116034 | 0.79 | PRCP (0.46) | PRCPGAAMAPTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL29116032 | 0.79 | PRCP (0.46) | PRCPGAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL13911781 | 0.78 | SMN1; SMN2 (0.55) | PRCPGAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL4240804 | 0.78 | SMN1; SMN2 (0.55) | PRCPGAAMAPTSMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL28391104 | 0.77 | SMN1; SMN2 (0.53) | PRCPGAAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL19580516 | 0.76 | HTR2C (0.42) | PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515949-B1 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2007-03-14 | — | — | EP | disclosed |
| EP-1515949-A4 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1515724-A4 | MITOTIC KINESIN INHIBITORS | MERCK & CO INC (US) | 2005-08-17 | — | — | EP | disclosed |
| EP-1515724-A1 | MITOTIC KINESIN INHIBITORS | Merck & Co., Inc. (US) | 2005-03-23 | — | — | EP | disclosed |
| EP-1515949-A1 | MITOTIC KINESIN INHIBITORS | Merck & Co., Inc. (US) | 2005-03-23 | — | — | EP | disclosed |
| WO-2004087050-A2 | MITOTIC KINESIN INHIBITORS | MERCK & CO., INC. (US) | 2004-10-14 | — | — | WO | disclosed |
| WO-2003105855-A1 | MITOTIC KINESIN INHIBITORS | MERCK & CO., INC. (US) | 2003-12-24 | — | — | WO | disclosed |
| WO-2003106417-A1 | MITOTIC KINESIN INHIBITORS | MERCK & CO., INC. (US) | 2003-12-24 | — | — | WO | disclosed |