Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13911781 | 1.00 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2ALMNAGAA | |
| Hydrochloric Acid SCHEMBL28391104 | 0.98 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2ALMNAGAA | |
| Ethylene SCHEMBL8557034 | 0.96 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2ALMNAGAA | |
| SCHEMBL6984427 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1KMT2ALMNAGAA | |
| SCHEMBL5738919 | 0.78 | PRCP (0.60) | SMN1; SMN2MEN1KMT2ALMNAGAA | |
| SCHEMBL13911779 | 0.78 | DDB1 (0.41) | SMN1; SMN2MEN1KMT2ALMNAGAA | |
| SCHEMBL6140740 | 0.78 | PRCP (0.60) | SMN1; SMN2MEN1KMT2ALMNAGAA | |
| Ethylene SCHEMBL8554182 | 0.78 | LMNA (0.45) | SMN1; SMN2MEN1KMT2ALMNAGAA | |
| SCHEMBL19283462 | 0.78 | MEN1 (0.64) | SMN1; SMN2MEN1KMT2ALMNAPRCP | |
| SCHEMBL29413705 | 0.77 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110963960-B | Compound for promoting watermelon expansion and watermelon expansion liquid fertilizer | 南京汉尔斯生物科技有限公司 | 2021-05-28 | — | — | CN | claimed |
| CN-110963960-A | Compound for promoting watermelon expansion and watermelon expansion liquid fertilizer | 南京汉尔斯生物科技有限公司 | 2020-04-07 | — | — | CN | claimed |
| CN-110963960-B | Compound for promoting watermelon expansion and watermelon expansion liquid fertilizer | 南京汉尔斯生物科技有限公司 | 2021-05-28 | — | — | CN | disclosed |
| CN-110963960-A | Compound for promoting watermelon expansion and watermelon expansion liquid fertilizer | 南京汉尔斯生物科技有限公司 | 2020-04-07 | — | — | CN | disclosed |
| US-9174960-B2 | Compounds useful against kinetoplastideae parasites | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-11-03 | — | — | US | disclosed |
| US-9174960-B2 | Compounds useful against kinetoplastideae parasites | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-11-03 | — | — | US | disclosed |
| EP-2664617-A1 | Method of making a 2,6-diaryl piperidine derivative | Genzyme Corporation (US) | 2013-11-20 | — | — | EP | disclosed |
| US-20120214996-A1 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-08-23 | — | — | US | disclosed |
| US-20120214996-A1 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-08-23 | — | — | US | disclosed |
| WO-2011033115-A2 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2011-03-24 | — | — | WO | disclosed |
| US-7501518-B2 | Methods of making 2,6-diaryl piperidine derivatives | GENZYME CORPORATION (US) | 2009-03-10 | — | — | US | disclosed |
| US-6420364-B1 | TREATING AUTOIMMUNE DISEASES,ALZHEIMER'S DISEASE, ATHEROSCLEROSIS, OSTEOPOROSIS, | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |
| EP-1218372-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| US-20020058809-A1 | Compounds useful as reversible inhibitors of cysteine proteases | EMMANUEL MICHEL JOSE (US) | 2002-05-16 | — | — | US | disclosed |
| WO-2001019816-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |
| EP-0567430-B1 | Substituted 1-Hydroxy-2,6-Diaryl-4-Piperidone Ketal Stabilizers | CIBA GEIGY AG (CH) | 1998-02-18 | — | — | EP | disclosed |
| EP-0567430-A1 | Substituted 1-Hydroxy-2,6-Diaryl-4-Piperidone Ketal Stabilizers | CIBA-GEIGY AG (CH) | 1993-10-27 | — | — | EP | disclosed |
| US-5235056-A | Discoloration inhibitors | CIBA-GEIGY CORPORATION (US) | 1993-08-10 | — | — | US | disclosed |
| EP-0056699-B1 | ORGANIC PEROXIDES AND USE OF SAME | AUSIMONT S.p.A. (IT) | 1986-04-09 | — | — | EP | disclosed |
| EP-0056699-A1 | Organic peroxides and use of same | AUSIMONT S.p.A. (IT) | 1982-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058809-A1 | Compounds useful as reversible inhibitors of cysteine proteases | CTSS, CTSK, CTSB | SMN1; SMN2 4666/4885MEN1 3318/4885KMT2A 4513/4885 |
| US-20120214996-A1 | COMPOUNDS USEFUL AGAINST KINETOPLASTIDEAE PARASITES | TST, PDXK, TBCB | SMN1; SMN2 3140/4885MEN1 4710/4885KMT2A 962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.