SCHEMBL6140846

SCHEMBL6140846

Cc1ccc(N)cc1.Cc1ccc(N)cc1.O=P(O)(O)Oc1cc2c(Cl)c(Br)ccc2[nH]1

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
HPGD P15428 2/20 0.33
GAA P10253 2/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALOX12 P18054 1/20 0.32
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5330341 1.00 ALDH1A1 (0.33) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL79536 0.88 DAO (0.33)
O-Tolylamine SCHEMBL9229915 0.84 MAP2 (0.33)
SCHEMBL79535 0.77 DAO (0.32)
Tetrazole SCHEMBL5041698 0.77
Tetrazole SCHEMBL3922918 0.77
Tetrazole SCHEMBL5041695 0.77
Tetrazole SCHEMBL6400674 0.76
SCHEMBL3739490 0.76 HTR2A (0.36) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL1474652 0.76 HTR2A (0.36) ALDH1A1MAPTMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6932968-B1 Erythropoietin (EPO) peptides and antibodies directed against these DADE BEHRING MARBURG GMBH (DE) 2005-08-23 US disclosed
EP-0748815-B1 Toxoplasma gondii antigen, its production and use DADE BEHRING MARBURG GMBH (DE) 2001-10-04 EP disclosed
EP-0751147-B1 Toxoplasma gondii antigen, its production and use DADE BEHRING MARBURG GMBH (DE) 2000-09-06 EP disclosed
US-5712370-A Erythropoietin (EPO) peptides and antibodies directed against these BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1998-01-27 US disclosed
EP-0751147-A1 Toxoplasma gondii antigen, its production and use BEHRINGWERKE Aktiengesellschaft (DE) 1997-01-02 EP disclosed
EP-0748815-A1 Toxoplasma gondii antigen, its production and use BEHRINGWERKE Aktiengesellschaft (DE) 1996-12-18 EP disclosed
US-5106954-A ERYTHROPOIETIN (EPO) PEPTIDES BEHRINGWERKE AKTIENGESELLSCHAFT (DE) 1992-04-21 US disclosed