Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28672682 | 0.80 | BACE1 (0.40) | BACE1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3863243 | 0.75 | HDAC4 (0.44) | HDAC3HDAC1HDAC2HDAC6HCAR2 | |
| SCHEMBL18742523 | 0.73 | BACE1 (0.38) | BACE1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL4245293 | 0.72 | BACE1 (0.42) | BACE1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL6141468 | 0.72 | MAOB (0.39) | — | |
| SCHEMBL10653193 | 0.72 | BACE1 (0.42) | BACE1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL7963641 | 0.72 | PSEN1 (0.41) | BACE1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29664671 | 0.71 | BACE1 (0.45) | BACE1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL9697435 | 0.71 | BACE1 (0.41) | BACE1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3849035 | 0.71 | BACE1 (0.45) | BACE1HDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517881-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | Syngenta Participations AG (CH) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004002943-A1 | 4-(3,3-DIHALO-ALLYLOXY)PHENOXY ALKYL DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-01-08 | — | — | WO | disclosed |