Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | AGXT | P21549 | 2/20 | 0.36 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653193 | 1.00 | BACE1 (0.42) | BACE1CNR1CES2CES1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14660865 | 0.85 | HTR2C (0.39) | BACE1CNR1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL3119870 | 0.79 | BACE1 (0.36) | BACE1CNR1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL14660769 | 0.78 | CNR1 (0.49) | BACE1CNR1CA6CA5ACA9 | |
| SCHEMBL3119906 | 0.77 | BACE1 (0.38) | BACE1CNR1ALDH1A1 | |
| SCHEMBL3122160 | 0.77 | CNR1 (0.40) | BACE1CNR1HDAC3HDAC1HDAC2 | |
| SCHEMBL9697435 | 0.76 | BACE1 (0.41) | BACE1CNR1CES2CES1ALDH1A1 | |
| SCHEMBL257533 | 0.76 | BACE1 (0.49) | BACE1CNR1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL29664671 | 0.76 | BACE1 (0.45) | BACE1ALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL3849035 | 0.76 | BACE1 (0.45) | BACE1ALDH1A1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7902227-B2 | C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents | JANSSEN PHARMACEUTICA NV. (BE) | 2011-03-08 | — | — | US | claimed |
| US-20090029980-A1 | C-7 Isoxazolinyl Quinolone / Naphthyridine Derivatives Useful as Antibacterial Agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2009-01-29 | — | — | US | claimed |
| EP-0278346-A1 | 1-(2,4-Difluorophenyl)-1-(1-fluorocyclopropyl)-2-(1,2,4-triazol-1-yl)-ethan-1-ol | BAYER AG (DE) | 1988-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029980-A1 | C-7 Isoxazolinyl Quinolone / Naphthyridine Derivatives Useful as Antibacterial Agents | CASP7, CYP3A7, NQO2 | BACE1 2642/4885CNR1 1350/4885CES2 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.