SCHEMBL6141471

SCHEMBL6141471

Cc1cc(N)ccc1NCc1ccccc1N1CCOCC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD9 Q9H8M2 5/20 0.54
BRD4 O60885 4/20 0.54
PIK3CD O00329 2/20 0.46
PIK3CA P42336 2/20 0.46
PIK3CB P42338 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.44
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
FGFR1 P11362 1/20 0.43
P2RX7 Q99572 1/20 0.43
PIK3CG P48736 1/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
TSHR P16473 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
LMNA P02545 1/20 0.42
ATM Q13315 1/20 0.42
ALDH1A1 P00352 3/20 0.41
MCOLN3 Q8TDD5 1/20 0.41
BRPF1 P55201 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2987094 0.99 BRD9 (0.53) BRD9BRD4PIK3CDPIK3CAPIK3CB
SCHEMBL7581625 0.83 BRD9 (0.48) BRD9BRD4SMN1; SMN2MAPTGAA
SCHEMBL6141837 0.83 BRD9 (0.47) BRD9BRD4SMN1; SMN2MAPTGAA
Hydrochloric Acid SCHEMBL2993545 0.82 BRD9 (0.46) BRD9BRD4SMN1; SMN2MAPTGAA
SCHEMBL6141865 0.80 P2RX7 (0.50) BRD9BRD4PIK3CDPIK3CAPIK3CB
Hydrochloric Acid SCHEMBL3072172 0.79 P2RX7 (0.49) BRD9BRD4PIK3CDPIK3CAPIK3CB
SCHEMBL6141829 0.79 GAA (0.49) BRD9BRD4PIK3CDPIK3CAPIK3CB
Hydrochloric Acid SCHEMBL2989438 0.78 GAA (0.48) BRD9BRD4PIK3CDPIK3CAPIK3CB
SCHEMBL6069709 0.77 BRD4 (0.44) BRD9BRD4SMN1; SMN2MAPTGAA
SCHEMBL6069736 0.76 BRD9 (0.46) BRD9BRD4SMN1; SMN2MAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1493731-A1 N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and these derivatives Wella Aktiengesellschaft (DE) 2005-01-05 EP disclosed
EP-1226107-A1 N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES Wella Aktiengesellschaft (DE) 2002-07-31 EP disclosed
WO-2002018318-A1 N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-07 WO disclosed