Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4148470 | 0.92 | PTGER1 (0.43) | PDGFRBPDGFRAMAPTHSD17B2CYP2C9 | |
| SCHEMBL4154876 | 0.86 | CA12 (0.42) | NPC1POLBMAPTTSHRRAB9A | |
| SCHEMBL5696668 | 0.80 | ALPL (0.42) | PDGFRBPDGFRANPC1POLBMAPT | |
| SCHEMBL4160158 | 0.80 | PTGER1 (0.65) | CYP2C9PTGER1 | |
| SCHEMBL5696865 | 0.78 | PTGER1 (0.47) | NPC1MAPTRAB9ASMN1; SMN2CYP2C9 | |
| SCHEMBL4924658 | 0.77 | CSF1R (0.42) | NPC1POLBMAPTTSHRRAB9A | |
| SCHEMBL4154318 | 0.75 | PTGER1 (0.42) | MAPTCYP2C9PTGER1ALDH1A1HPGD | |
| SCHEMBL4158329 | 0.75 | PTGER1 (0.42) | MAPTSMN1; SMN2CYP2C9PTGER1ALDH1A1 | |
| SCHEMBL6140573 | 0.75 | CA12 (0.41) | NPC1MAPTRAB9ASMN1; SMN2HSD17B10 | |
| SCHEMBL5619619 | 0.74 | PTGER1 (0.45) | NPC1POLBMAPTTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492757-A1 | (2-((2-ALKOXY)-PHENYL)-CYCLOPENT-1-ENYL) AROMATIC CARBO- AND HETEROCYCLIC CARBOXYLIC ACID AND DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084917-A1 | (2-((2-ALKOXY) -PHENYL) -CYCLOPENT-1-ENYL) AROMATIC CARBO AND HETEROCYCLIC ACID AND DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-10-16 | — | — | WO | disclosed |