Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | HTT | P42858 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.54 |
| ▸ | CDK2 | P24941 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 6/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29524840 | 1.00 | CYP3A4 (0.68) | CYP3A4HTTLMNACYP1A2CDK2 | |
| SCHEMBL30320038 | 0.94 | CYP3A4 (0.60) | CYP3A4HTTLMNACYP1A2CDK2 | |
| SCHEMBL150047 | 0.86 | HTT (0.70) | CYP3A4HTTLMNACYP1A2CDK2 | |
| SCHEMBL29612168 | 0.86 | HTT (0.70) | CYP3A4HTTLMNACYP1A2CDK2 | |
| SCHEMBL10344772 | 0.82 | HTT (0.60) | CYP3A4HTTLMNACYP1A2CDK2 | |
| SCHEMBL5628458 | 0.81 | HTT (0.63) | CYP3A4HTTLMNACYP1A2CDK2 | |
| SCHEMBL7668701 | 0.81 | CYP3A4 (1.00) | CYP3A4HTTLMNACYP1A2CDK2 | |
| SCHEMBL6141603 | 0.80 | CYP1A2 (0.41) | CYP3A4HTTLMNACYP1A2CDK2 | |
| SCHEMBL25176526 | 0.78 | SMN1; SMN2 (0.54) | CYP3A4HTTLMNACYP1A2CDK2 | |
| SCHEMBL9201457 | 0.78 | HTT (1.00) | CYP3A4HTTLMNACYP1A2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4472642-A1 | HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2024-12-11 | — | — | EP | claimed |
| EP-4153592-B1 | MESYLATE SALTS OF HETEROCYCLIC CYTOKININS, COMPOSITIONS CONTAINING THESE DERIVATIVES AND USE THEREOF | UNIV PALACKEHO (CZ) | 2024-04-24 | — | — | EP | claimed |
| WO-2023078482-A1 | HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-05-11 | — | — | WO | claimed |
| EP-0884293-B1 | Fertiliser compositions containing natural or synthetic aminopurine derivatives or seaweed extracts containing these products together with a calcium source | SECMA BIOTECHNOLOGIES MARINES (FR) | 2005-01-05 | — | — | EP | claimed |
| EP-4472642-A1 | HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2024-12-11 | — | — | EP | disclosed |
| WO-2023078482-A1 | HETEROCYCLIC PURINE CYTOKININ DERIVATIVES, THEIR USE IN WOUND HEALING AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-05-11 | — | — | WO | disclosed |