Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 1/20 | 0.67 |
| ▸ | BRD4 | O60885 | 1/20 | 0.67 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.67 |
| ▸ | CA2 | P00918 | 1/20 | 0.67 |
| ▸ | MB | P02144 | 1/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.67 |
| ▸ | CA3 | P07451 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | RARG | P13631 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4647437 | 0.93 | TDP1 (0.87) | TDP1PKMSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL11244788 | 0.93 | TDP1 (0.87) | TDP1PKMSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL861674 | 0.89 | SMN1; SMN2 (0.84) | TDP1SMN1; SMN2L3MBTL1HTTKMT2A | |
| SCHEMBL5612841 | 0.88 | TDP1 (0.77) | TDP1PKMSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL14384400 | 0.88 | TDP1 (0.77) | TDP1PKMSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL12620630 | 0.88 | TDP1 (0.77) | TDP1PKMSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL8737881 | 0.88 | TDP1 (0.77) | TDP1PKMSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL18405965 | 0.88 | TDP1 (0.77) | TDP1PKMSMN1; SMN2L3MBTL1HTT | |
| SCHEMBL12259233 | 0.88 | NPC1 (0.85) | TDP1PKMSMN1; SMN2L3MBTL1KMT2A | |
| SCHEMBL4199168 | 0.88 | TDP1 (0.77) | TDP1PKMSMN1; SMN2L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2217 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240383909-A1 | CO-CRYSTALS | INTRA-CELLULAR THERAPIES, INC. | 2024-11-21 | — | — | US | claimed |
| EP-4395767-A2 | CO-CRYSTALS | Intra-Cellular Therapies, Inc. (US) | 2024-07-10 | — | — | EP | claimed |
| CN-117732278-A | Desalination separation membrane and preparation method and application thereof | 江南大学 | 2024-03-22 | — | — | CN | claimed |
| CN-113773221-B | P-benzoquinone compound and preparation method thereof | 湖北工业大学 | 2023-09-29 | — | — | CN | claimed |
| CN-114573582-B | 1,2,3, 4-tetrahydropyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2023-06-16 | — | — | CN | claimed |
| WO-2023034965-A2 | CO-CRYSTALS | INTRA-CELLULAR THERAPIES, INC. (US) | 2023-03-09 | — | — | WO | claimed |
| US-11424006-B2 | Targeted drugs associated with trimethylamine and/or trimeihylamine-n-oxide | PSOMAGEN, INC. (US) | 2022-08-23 | — | — | US | claimed |
| CN-114573582-A | 1,2,3, 4-tetrahydropyrido [2,3-d ] pyrimidine compound and preparation method and application thereof | 沈阳药科大学 | 2022-06-03 | — | — | CN | claimed |
| CN-113999130-A | Preparation method of o-nitroanilide compound | 湖北工业大学 | 2022-02-01 | — | — | CN | claimed |
| CN-113773221-A | P-benzoquinone compound and preparation method thereof | 湖北工业大学 | 2021-12-10 | — | — | CN | claimed |
| CN-1052299-A | From the mixture that contains aromatic ketone, remove hydrofluoric method | HOECHST CELANESE CORP (US) | 1991-06-19 | — | — | CN | claimed |
| US-4600797-A | NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-15 | — | — | US | claimed |
| EP-0053890-B1 | PRODUCTION OF ARYL ACYLAMIDASES | The Public Health Laboratory Service Board (GB) | 1985-02-13 | — | — | EP | claimed |
| US-4430433-A | CULTURES, PSEUDOMONAS, HYDROLYSIS OF N-ACETYL-4-HYDROXYANILINE TO 4-HYDROXYANILINE | PUBLIC HEALTH LABORATORY SERVICE BOARD (GB) | 1984-02-07 | — | — | US | claimed |
| US-4394309-A | Process for the preparation of N,N-dimethyl-N-(2-bromo-4-methylphenyl)-triazene | BAYER AKTIENGESELLSCHAFT (DE) | 1983-07-19 | — | — | US | claimed |
| EP-0037948-B1 | PROCESS FOR PREPARING N,N'-DIMETHYL-N'-(2-BROMO-4-METHYLPHENYL) TRIAZENE | BAYER AG (DE) | 1983-04-20 | — | — | EP | claimed |
| EP-0027658-B1 | PROCESS FOR THE PRODUCTION OF 3-NITRO-4-AMINOTOLUENE | BAYER AG (DE) | 1982-05-26 | — | — | EP | claimed |
| EP-0037948-A1 | Process for preparing N,N'-dimethyl-N'-(2-bromo-4-methylphenyl) triazene | BAYER AG (DE) | 1981-10-21 | — | — | EP | claimed |
| EP-0027658-A1 | Process for the production of 3-nitro-4-aminotoluene | BAYER AG (DE) | 1981-04-29 | — | — | EP | claimed |
| US-4220601-A | Process for the continuous manufacture of 3-nitro-4-acetylamino-toluene and corresponding apparatus | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-09-02 | — | — | US | claimed |