SCHEMBL6141920

SCHEMBL6141920

Cc1cc(N)ccc1NCc1cccc(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.50
CYP3A4 P08684 2/20 0.50
PKM P14618 1/20 0.50
ALOX15 P16050 1/20 0.50
NFKB1 P19838 1/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 6/20 0.49
KMT2A Q03164 4/20 0.49
KDM4E B2RXH2 1/20 0.49
LMNA P02545 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49
MEN1 O00255 3/20 0.47
DRD2 P14416 1/20 0.44
DRD1 P21728 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
ENPP2 Q13822 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
ALDH1A1 P00352 3/20 0.42
CRHBP P24387 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2989202 0.99 MAPT (0.51) CYP1A2CYP3A4PKMALOX15NFKB1
SCHEMBL6259279 0.83 TNIK (0.49) CYP1A2CYP3A4ALOX15MAPK1MAPT
Hydrochloric Acid SCHEMBL2990577 0.82 TNIK (0.48) CYP1A2CYP3A4ALOX15MAPK1MAPT
SCHEMBL6069372 0.79 CYP1A2 (0.50) CYP1A2CYP3A4PKMALOX15NFKB1
SCHEMBL7560152 0.79 MAPT (0.47) CYP1A2CYP3A4MAPTKMT2ALMNA
SCHEMBL6069254 0.79 MAPT (0.51) CYP1A2CYP3A4PKMALOX15NFKB1
SCHEMBL6141857 0.78 ALDH1A1 (0.42) CYP1A2CYP3A4MAPTKMT2ALMNA
SCHEMBL5268695 0.77 MAPT (0.48) CYP1A2CYP3A4MAPK1MAPTKMT2A
SCHEMBL2940046 0.76 HIF1A (0.61) CYP1A2CYP3A4PKMALOX15NFKB1
Resorcinol SCHEMBL11793128 0.76 ALDH1A1 (0.48) CYP1A2CYP3A4ALOX15MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1493731-A1 N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and these derivatives Wella Aktiengesellschaft (DE) 2005-01-05 EP disclosed
EP-1226107-A1 N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES Wella Aktiengesellschaft (DE) 2002-07-31 EP disclosed
WO-2002018318-A1 N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES CONTAINING COLOURING AGENTS FOR KERATIN FIBRES AND NOVEL N-BENZYL-P-PHENYLENEDIAMINE-DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-07 WO disclosed