Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.40 |
| ▸ | ECE1 | P42892 | 4/20 | 0.38 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6141964 | 1.00 | DPP4 (0.40) | DPP4DPP8DPP9ECE1PDCD1LG2 | |
| SCHEMBL8525692 | 0.85 | DPP4 (0.40) | DPP4DPP8DPP9 | |
| SCHEMBL9351970 | 0.83 | SLC7A5 (0.47) | DPP4DPP8DPP9 | |
| SCHEMBL1797328 | 0.83 | SLC7A5 (0.47) | DPP4DPP8DPP9 | |
| SCHEMBL1031740 | 0.81 | DPP4 (0.38) | DPP4DPP8DPP9PDCD1LG2CD274 | |
| SCHEMBL10891150 | 0.80 | DPP4 (0.44) | DPP4DPP8DPP9ECE1PDCD1LG2 | |
| SCHEMBL10888528 | 0.80 | DPP4 (0.44) | DPP4DPP8DPP9ECE1PDCD1LG2 | |
| SCHEMBL6141906 | 0.80 | DPP4 (0.36) | DPP4DPP8DPP9ECE1PDCD1LG2 | |
| SCHEMBL6141907 | 0.80 | DPP4 (0.36) | DPP4DPP8DPP9ECE1PDCD1LG2 | |
| SCHEMBL27646824 | 0.79 | CTSC (0.34) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1493815-A1 | Novel fusion protein recovery and purification methods | Genetics Institute, LLC (US) | 2005-01-05 | — | — | EP | disclosed |
| EP-0828842-B1 | NOVEL FUSION PROTEIN RECOVERY AND PURIFICATION METHODS | INST GENETICS LLC (US) | 2004-10-06 | — | — | EP | disclosed |
| US-5760189-A | CHROMATOGRAPHIC SEPARATION | GENETICS INSTITUTE, INC. (US) | 1998-06-02 | — | — | US | disclosed |
| EP-0828842-A1 | NOVEL FUSION PROTEIN RECOVERY AND PURIFICATION METHODS | GENETICS INSTITUTE, INC. (US) | 1998-03-18 | — | — | EP | disclosed |
| WO-1996038570-A1 | NOVEL FUSION PROTEIN RECOVERY AND PURIFICATION METHODS | GENETICS INSTITUTE, INC. (US) | 1996-12-05 | — | — | WO | disclosed |