SCHEMBL8525692

SCHEMBL8525692

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nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.40
DPP8 Q6V1X1 2/20 0.40
DPP9 Q86TI2 2/20 0.40
BHMT Q93088 1/20 0.34
S1PR1 P21453 1/20 0.34
S1PR3 Q99500 1/20 0.34
LTA4H P09960 2/20 0.33
MME P08473 2/20 0.33
CACNA2D1 P54289 2/20 0.32
GABRP O00591 2/20 0.32
GABRD O14764 2/20 0.32
GABRA1 P14867 2/20 0.32
GABRB1 P18505 2/20 0.32
GABRG2 P18507 2/20 0.32
GABRB3 P28472 2/20 0.32
GABRA5 P31644 2/20 0.32
GABRA3 P34903 2/20 0.32
GABRA2 P47869 2/20 0.32
GABRB2 P47870 2/20 0.32
GABRA4 P48169 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6141967 0.85 DPP4 (0.40) DPP4DPP8DPP9
SCHEMBL6141964 0.85 DPP4 (0.40) DPP4DPP8DPP9
SCHEMBL1797328 0.83 SLC7A5 (0.47) DPP4DPP8DPP9SLC7A5
SCHEMBL9351970 0.83 SLC7A5 (0.47) DPP4DPP8DPP9SLC7A5
SCHEMBL27262388 0.82 DPP4 (0.61) DPP4DPP8DPP9S1PR1S1PR3
SCHEMBL10943106 0.82 DPP4 (0.61) DPP4DPP8DPP9S1PR1S1PR3
SCHEMBL2182252 0.82 DPP4 (0.38) DPP4DPP8DPP9BHMTS1PR1
SCHEMBL1031740 0.81 DPP4 (0.38) DPP4DPP8DPP9
SCHEMBL24270547 0.80 DPP4 (0.44) DPP4DPP8DPP9BHMTS1PR1
SCHEMBL10801006 0.80 DPP4 (0.44) DPP4DPP8DPP9BHMTS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0885899-A1 Method for obtaining peptide fragments by use of fluorinated organic acids SEIKO INSTRUMENTS INC. (JP) 1998-12-23 EP disclosed