Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | GAA | P10253 | 3/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | GSK3B | P49841 | 3/20 | 0.56 |
| ▸ | CDC7 | O00311 | 2/20 | 0.56 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.56 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13936247 | 0.87 | KMT2A (0.62) | PAX8KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL28606256 | 0.79 | KMT2A (0.76) | PAX8KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL30019922 | 0.77 | KMT2A (1.00) | PAX8KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL13848480 | 0.77 | KMT2A (1.00) | PAX8KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8994653 | 0.76 | KMT2A (0.76) | PAX8KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL2024634 | 0.76 | ALDH1A1 (0.51) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL15421615 | 0.75 | ALDH1A1 (0.80) | PAX8KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL24510580 | 0.74 | MAPT (1.00) | PAX8KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL6851610 | 0.74 | MAPT (1.00) | PAX8KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL29857079 | 0.74 | MAPT (1.00) | PAX8KMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1882602-A | Modulation and degradation of hyaluronan synthesis in the treatment of disease | MEDITECH RES LTD (AU) | 2006-12-20 | — | — | CN | claimed |
| EP-1575539-A1 | DYE TABLETS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004058202-A1 | DYE TABLETS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | claimed |
| CN-1761517-A | Mixing device | HENKEL KGAA (DE) | 2006-04-19 | — | — | CN | disclosed |
| EP-1575539-A1 | DYE TABLETS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004058202-A1 | DYE TABLETS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | disclosed |