Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6143081 | 1.00 | — | — | |
| SCHEMBL2321562 | 0.98 | — | — | |
| SCHEMBL5771317 | 0.98 | — | — | |
| SCHEMBL890174 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL6147870 | 0.95 | — | — | |
| SCHEMBL10367186 | 0.91 | — | — | |
| SCHEMBL18731092 | 0.91 | — | — | |
| SCHEMBL17928477 | 0.85 | — | — | |
| SCHEMBL6143108 | 0.77 | NOS2 (0.52) | — | |
| SCHEMBL6143295 | 0.77 | NOS2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318148-B1 | Method of preparing optically pure (R)- or (S)- tetrahydrofuranyl ketone | SK CORP (KR) | 2005-01-12 | — | — | EP | disclosed |
| US-6841688-B2 | Method of preparing optically pure (R)- or (S)- tetrahydrofuranyl ketone | SK CORPORATION (KR) | 2005-01-11 | — | — | US | disclosed |
| US-20030114693-A1 | Method of preparing optically pure (R) - or (S) - tetrahydrofuranyl ketone | SK CORPORATION | 2003-06-19 | — | — | US | disclosed |
| EP-1318148-A1 | Method of preparing optically pure (R)- or (S)- tetrahydrofuranyl ketone | SK Corporation (KR) | 2003-06-11 | — | — | EP | disclosed |