Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28897693 | 0.88 | TSHR (0.43) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL15443233 | 0.84 | TSHR (0.40) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL28418030 | 0.82 | TSHR (0.39) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL8980120 | 0.82 | TSHR (0.39) | TSHRLMNAALOX15HCAR2 | |
| SCHEMBL15015655 | 0.80 | TSHR (0.37) | TSHRLMNAALOX15HCAR2MAPT | |
| SCHEMBL3700073 | 0.79 | ALDH1A1 (0.42) | TSHRLMNAALOX15 | |
| SCHEMBL30561836 | 0.79 | CA1 (0.42) | TSHR | |
| SCHEMBL638162 | 0.79 | ALDH1A1 (0.42) | TSHRLMNAALOX15 | |
| SCHEMBL18359202 | 0.79 | CA1 (0.42) | TSHR | |
| SCHEMBL5079956 | 0.79 | CA1 (0.42) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492764-A2 | NEW PROCESS | AstraZeneca AB (SE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003082812-A2 | PROCESS FOR THE PREPARATION OF 2-ETHOXY-3-[4-(2-{METHANESULPHONYLOXYPHENYL}ETHOXY) PHENIL] PROPANOIC ACID | ASTRAZENECA AB (SE) | 2003-10-09 | — | — | WO | disclosed |