SCHEMBL614455

SCHEMBL614455

C=CCC(F)(F)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7379533 1.00
Hydrochloric Acid SCHEMBL10414692 0.97 ALDH1A1 (0.41)
SCHEMBL6390835 0.97 ALDH1A1 (0.41)
SCHEMBL16843453 0.80 ALDH1A1 (0.35)
SCHEMBL9723013 0.79 ALDH1A1 (0.42)
SCHEMBL3214356 0.79
SCHEMBL5936843 0.79 ALDH1A1 (0.42)
SCHEMBL2361075 0.78 ALDH1A1 (0.35)
SCHEMBL7371095 0.77
SCHEMBL15116664 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110911750-B High-voltage lithium ion battery electrolyte, additive and preparation method of additive 珠海市赛纬电子材料股份有限公司 2022-06-24 CN claimed
CN-110911750-A High-voltage lithium ion battery electrolyte, additive and preparation method of additive 珠海市赛纬电子材料股份有限公司 2020-03-24 CN claimed
US-12404274-B2 Macrocycles as factor xia inhibitors BRISTOL-MYERS SQUIBB COMPANY (US) 2025-09-02 US disclosed
CN-120077028-A Thiadiazole derivative, composition and application thereof 北京丹擎医药科技有限公司 2025-05-30 CN disclosed
US-12297205-B2 Macrocyclic compounds for treatment of medical disorders ACHILLION PHARMACEUTICALS, INC. (US) 2025-05-13 US disclosed
CN-118480003-A Preparation method of fluoroalkylated quinoline diketone compound 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2024-08-13 CN disclosed
WO-2024099337-A1 THIADIAZOLYL DERIVATIVES, COMPOSITIONS, AND USES THEREOF DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2024-05-16 WO disclosed
US-20240059702-A1 MACROCYCLIC COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS ACHILLION PHARMACEUTICALS, INC. (US) 2024-02-22 US disclosed
US-11891404-B2 Substituted macrocyclic indole derivatives BAYER AKTIENGESELLSCHAFT (DE) 2024-02-06 US disclosed
CN-111757884-B Substituted macrocyclic indole derivatives 拜耳股份公司 2023-12-19 CN disclosed
US-20230348439-A1 INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS NIDO BIOSCIENCES INC (US) 2023-11-02 US disclosed
EP-0451835-A1 Intermediates for difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases MERRELL DOW PHARMACEUTICALS INC. (US) 1991-10-16 EP disclosed
EP-0451836-A2 Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases HEALTH RESEARCH INCORPORATED (US) 1991-10-16 EP disclosed
US-4892962-A FROM ALLYL DIFLUOROACETATES AND A MONOCHLORO=SILANE, ADDITION POLYMERS CIBA-GEIGY CORPORATION (US) 1990-01-09 US disclosed
US-4892962-A FROM ALLYL DIFLUOROACETATES AND A MONOCHLORO=SILANE, ADDITION POLYMERS CIBA-GEIGY CORPORATION (US) 1990-01-09 US disclosed
US-4847401-A Continuous large-scale production of ethyl 2,2-difluoro-4-pentenoate and 2-fluorinated methyl aminoacetonitriles by use of a flow reactor MERRELL DOW PHARMACEUTICALS INC. (US) 1989-07-11 US disclosed
EP-0230144-B1 FLOW REACTOR SYSTEM MERRELL DOW PHARMACEUTICALS INC. (US) 1989-03-29 EP disclosed
EP-0273008-A2 Process for the preparation of 2,2-difluoropent-4-ene-carboxylic acids and derivatives CIBA-GEIGY AG (CH) 1988-06-29 EP disclosed
EP-0230144-A1 Flow reactor system MERRELL DOW PHARMACEUTICALS INC. (US) 1987-07-29 EP disclosed
EP-0195212-A2 Novel peptidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1986-09-24 EP disclosed