SCHEMBL6144569

SCHEMBL6144569

Cc1cc(SCCc2cn(-c3ccc(C(F)(F)F)cc3)nc2C(C)(C)C)ccc1OCC(=O)O

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.55
PPARA Q07869 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5904809 0.91 PPARD (0.59) PPARDPPARA
SCHEMBL3964310 0.86 PPARD (0.52) PPARDPPARA
SCHEMBL5904863 0.84 PPARD (0.57) PPARDPPARA
SCHEMBL5004906 0.84 PPARD (0.61) PPARDPPARA
SCHEMBL5904654 0.84 PPARD (0.52) PPARDPPARA
SCHEMBL4952004 0.81 PPARD (0.57) PPARDPPARA
SCHEMBL5904620 0.81 PPARD (0.58) PPARDPPARA
SCHEMBL5904854 0.79 PPARD (0.54) PPARDPPARA
SCHEMBL5904913 0.79 PPARD (0.53) PPARDPPARA
SCHEMBL3963609 0.79 PPARD (0.57) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1585733-A1 HETEROCYCLIC PPAR MODULATORS ELI LILLY AND COMPANY (US) 2005-10-19 EP disclosed
WO-2004063166-A1 HETEROCYCLIC PPAR MODULATORS ELI LILLY AND COMPANY (US) 2004-07-29 WO disclosed