Bicarbonate

Bicarbonate

SCHEMBL614487

O.O.O=C(O)O.[Cu].[Cu].[Zn]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL614490 1.00
Bicarbonate SCHEMBL15189592 0.94
Bicarbonate SCHEMBL8054445 0.94
Bicarbonate SCHEMBL437196 0.94
Bicarbonate SCHEMBL9301406 0.94 CA1 (0.71)
Bicarbonate SCHEMBL5558106 0.94
Bicarbonate SCHEMBL614489 0.94
Bicarbonate SCHEMBL10804016 0.94
Bicarbonate SCHEMBL5750297 0.94
Bicarbonate SCHEMBL9576854 0.94 CA1 (0.71)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 807 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1603521-B1 AUGMENTATION OF PYRITHIONE ACTIVITY OR A POLYVALENT METAL SALT OF PYRITHIONE ACTIVITY BY ZINC-CONTAINING LAYERED MATERIAL PROCTER & GAMBLE (US) 2020-06-17 EP claimed
EP-2763653-B1 PERSONAL CARE COMPOSITIONS AND METHODS OF MAKING SAME PROCTER & GAMBLE (US) 2019-07-17 EP claimed
EP-2999455-B1 METHOD OF ACHIEVING IMPROVED PRODUCT RHEOLOGY, COSMETIC CONSUMER ACCEPTANCE AND DEPOSITION PROCTER & GAMBLE (US) 2019-05-15 EP claimed
EP-2953686-B1 HAIR CARE COMPOSITION COMPRISING CATIONIC POLYMERS AND ANIONIC PARTICULATES PROCTER & GAMBLE (US) 2019-03-27 EP claimed
CN-105338953-B Method for achieving improved product rheology, cosmetic consumer acceptance and deposition 宝洁公司 2018-09-28 CN claimed
US-9662291-B2 Method of achieving improved hair feel THE PROCTER & GAMBLE COMPANY (US) 2017-05-30 US claimed
US-9381148-B2 Composition comprising particulate zinc material with a high relative zinc lability THE PROCTER & GAMBLE COMPANY (US) 2016-07-05 US claimed
US-9381382-B2 Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a gel network THE PROCTER & GAMBLE COMPANY (US) 2016-07-05 US claimed
US-20160143835-A1 METHOD OF ACHIEVING IMPROVED HAIR FEEL PROCTER & GAMBLE (US) 2016-05-26 US claimed
EP-2999455-A1 METHOD OF ACHIEVING IMPROVED PRODUCT RHEOLOGY, COSMETIC CONSUMER ACCEPTANCE AND DEPOSITION The Procter & Gamble Company (US) 2016-03-30 EP claimed
US-20040223941-A1 Composition comprising zinc-containing layered material with a high relative zinc lability THE PROCTER & GAMBLE 2004-11-11 US claimed
CN-1543434-A Compositions and methods for treating cells and plants 沃尔特・H・冉克斯 2004-11-03 CN claimed
US-20040213751-A1 zinc pyrithione or pyrithione and a zinc-containing layered material selected from basic zinc carbonate, zinc carbonate hydroxide, hydrozincite, zinc copper carbonate hydroxide, aurichalcite, copper zinc carbonate hydroxide etc. for treating microbial and fungal infections on the skin or scalp ARCH CHEMICALS, INC. 2004-10-28 US claimed
US-20040191331-A1 Composition comprising particulate zinc materials having a defined crystallite size THE PROCTER & GAMBLE COMPANY 2004-09-30 US claimed
WO-2004082649-A1 AUGMENTATION OF PYRITHIONE ACTIVITY OR A POLYVALENT METAL SALT OF PYRITHIONE ACTIVITY BY ZINC-CONTAINING LAYERED MATERIAL THE PROCTER & GAMBLE COMPANY (US) 2004-09-30 WO claimed
WO-2004082648-A1 COMPOSITION COMPRISING PARTICULATE ZINC MATERIALS HAVING A DEFINED CRYSTALLITE SIZE THE PROCTER & GAMBLE COMPANY (US) 2004-09-30 WO claimed
WO-2004082647-A1 COMPOSITION COMPRISING ZINC-CONTAINING LAYERED MATERIAL WITH A HIGH RELATIVE ZINC LABILITY THE PROCTER & GAMBLE COMPANY (US) 2004-09-30 WO claimed
EP-1412284-A2 COMPOSITION FOR TREATING CELLS AND METHODS FOR QUALITATIVELY AND QUANTITATIVELY CUSTOMIZING THE FORMULATION THEREOF FOR A HEURISTICALLY DERIVED LIVING CELL NUTRIENT-COMPOSITION-ON-DEMAND Runkis, Walter H. (US) 2004-04-28 EP claimed
US-20030073580-A1 Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof RUNKIS WALTER H (US) 2003-04-17 US claimed
WO-2002100772-A2 COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS RUNKIS WALTER H (US) 2002-12-19 WO claimed