Bicarbonate

Bicarbonate

SCHEMBL614490

O.O=C(O)O.[Cu].[Zn]

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL614487 1.00
Bicarbonate SCHEMBL15189592 0.94
Bicarbonate SCHEMBL8054445 0.94
Bicarbonate SCHEMBL437196 0.94
Bicarbonate SCHEMBL9301406 0.94 CA1 (0.71)
Bicarbonate SCHEMBL5558106 0.94
Bicarbonate SCHEMBL614489 0.94
Bicarbonate SCHEMBL10804016 0.94
Bicarbonate SCHEMBL5750297 0.94
Bicarbonate SCHEMBL9576854 0.94 CA1 (0.71)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 826 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1496899-B1 USE OF MATERIALS HAVING ZINC IONOPHORIC BEHAVIOR PROCTER & GAMBLE (US) 2021-06-23 EP claimed
EP-1603521-B1 AUGMENTATION OF PYRITHIONE ACTIVITY OR A POLYVALENT METAL SALT OF PYRITHIONE ACTIVITY BY ZINC-CONTAINING LAYERED MATERIAL PROCTER & GAMBLE (US) 2020-06-17 EP claimed
EP-2763653-B1 PERSONAL CARE COMPOSITIONS AND METHODS OF MAKING SAME PROCTER & GAMBLE (US) 2019-07-17 EP claimed
EP-2999455-B1 METHOD OF ACHIEVING IMPROVED PRODUCT RHEOLOGY, COSMETIC CONSUMER ACCEPTANCE AND DEPOSITION PROCTER & GAMBLE (US) 2019-05-15 EP claimed
EP-2953686-B1 HAIR CARE COMPOSITION COMPRISING CATIONIC POLYMERS AND ANIONIC PARTICULATES PROCTER & GAMBLE (US) 2019-03-27 EP claimed
CN-105338953-B Method for achieving improved product rheology, cosmetic consumer acceptance and deposition 宝洁公司 2018-09-28 CN claimed
US-9662291-B2 Method of achieving improved hair feel THE PROCTER & GAMBLE COMPANY (US) 2017-05-30 US claimed
CN-103857380-B The method obtaining the trichoesthesia improved 宝洁公司 2016-08-17 CN claimed
US-9381148-B2 Composition comprising particulate zinc material with a high relative zinc lability THE PROCTER & GAMBLE COMPANY (US) 2016-07-05 US claimed
US-9381382-B2 Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a gel network THE PROCTER & GAMBLE COMPANY (US) 2016-07-05 US claimed
US-20040191331-A1 Composition comprising particulate zinc materials having a defined crystallite size THE PROCTER & GAMBLE COMPANY 2004-09-30 US claimed
WO-2004082649-A1 AUGMENTATION OF PYRITHIONE ACTIVITY OR A POLYVALENT METAL SALT OF PYRITHIONE ACTIVITY BY ZINC-CONTAINING LAYERED MATERIAL THE PROCTER & GAMBLE COMPANY (US) 2004-09-30 WO claimed
WO-2004082648-A1 COMPOSITION COMPRISING PARTICULATE ZINC MATERIALS HAVING A DEFINED CRYSTALLITE SIZE THE PROCTER & GAMBLE COMPANY (US) 2004-09-30 WO claimed
EP-1412284-A2 COMPOSITION FOR TREATING CELLS AND METHODS FOR QUALITATIVELY AND QUANTITATIVELY CUSTOMIZING THE FORMULATION THEREOF FOR A HEURISTICALLY DERIVED LIVING CELL NUTRIENT-COMPOSITION-ON-DEMAND Runkis, Walter H. (US) 2004-04-28 EP claimed
US-20040058855-A1 Use of materials having zinc ionophoric behavior THE PROCTOR & GAMBLE COMPANY 2004-03-25 US claimed
US-20030215522-A1 Personal care compositions comprising a zinc containing material in an aqueous surfactant composition THE PROCTER & GAMBLE COMPANY 2003-11-20 US claimed
WO-2003088965-A1 USE OF MATERIALS HAVING ZINC IONOPHORIC BEHAVIOR THE PROCTER & GAMBLE COMPANY (US) 2003-10-30 WO claimed
WO-2003088957-A1 PERSONAL CARE COMPOSITIONS COMPRISING A ZINC CONTAINING MATERIAL IN AN AQUEOUS SURFACTANT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2003-10-30 WO claimed
US-20030073580-A1 Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof RUNKIS WALTER H (US) 2003-04-17 US claimed
WO-2002100772-A2 COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS RUNKIS WALTER H (US) 2002-12-19 WO claimed