SCHEMBL614666

SCHEMBL614666

CO[Si](CCCN1CCCCC1)(OC)OC

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 5/20 0.50
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
CYP1A2 P05177 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KCNH2 Q12809 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HRH1 P35367 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1229250 1.00 HRH3 (0.50) HRH3POLBMAPTCYP1A2ALDH1A1
SCHEMBL329772 0.98 HRH3 (0.46) HRH3POLBMAPTCYP1A2ALDH1A1
SCHEMBL11897301 0.89 MAPT (0.37) MAPTKCNH2
SCHEMBL4361438 0.89 MAPT (0.37) MAPTKCNH2
SCHEMBL1459032 0.87 HRH3 (0.42) HRH3POLBMAPTALDH1A1KMT2A
SCHEMBL995927 0.87 HRH3 (0.42) HRH3POLBMAPTALDH1A1KMT2A
SCHEMBL11897271 0.86 KDM4E (0.35) HRH3POLBMAPTCYP1A2ALDH1A1
SCHEMBL12802639 0.85 HRH3 (0.41) HRH3POLBCYP1A2ALDH1A1KMT2A
SCHEMBL10598698 0.83 KCNH2 (0.40) HRH3MAPTKCNH2
SCHEMBL302762 0.83 CSNK2A2 (0.43) HRH3MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103467745-B The preparation method of terminal alkoxy polysiloxane CHENGDU GUIBAO SCIENCE AND TECHNOLOGY INDUSTRIAL CO., LTD. (CN) 2015-08-05 CN claimed
EP-0417755-B1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO LTD (JP) 1993-12-29 EP claimed
US-5103000-A PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME DAISO CO., LTD. (JP) 1992-04-07 US claimed
EP-0417755-A1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO., LTD. (JP) 1991-03-20 EP claimed
EP-3950724-B1 CONJUGATED DIENE COPOLYMER AND METHOD FOR MANUFACTURING CONJUGATED DIENE COPOLYMER ZEON CORP (JP) 2026-02-18 EP disclosed
US-20250256980-A1 METAL OXIDE PARTICLE HAVING CORE-SHELL STRUCTURE AND METHOD FOR PRODUCING SAME NISSAN CHEMICAL CORPORATION (JP) 2025-08-14 US disclosed
CN-119968338-A Organic solvent sol containing hollow silica particles of amine and method for producing same 日产化学株式会社 2025-05-09 CN disclosed
CN-119894824-A Hollow silica sol containing 1-valent alkali metal ion and method for producing same 日产化学株式会社 2025-04-25 CN disclosed
CN-118055985-B Composition containing metal oxide particles with reduced production of volatile aldehydes 日产化学株式会社 2025-04-01 CN disclosed
CN-119301070-A Metal oxide particle having core-shell structure and method for producing same 日产化学株式会社 2025-01-10 CN disclosed
CN-119053553-A Organic solvent dispersion sol containing conductive tin oxide particles and method for producing same 日产化学株式会社 2024-11-29 CN disclosed
US-12139572-B2 Conjugated diene copolymer and method for manufacturing conjugated diene copolymer ZS ELASTOMERS CO., LTD. (JP) 2024-11-12 US disclosed
US-5811479-A TIRE TREADS WITH IMPROVED HYSTERESIS PROPERTIES COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELINE - MICHELIN & CIE 1998-09-22 US disclosed
US-5789127-A Electrophotographic photoreceptor FUJI XEROX CO., LTD. (JP) 1998-08-04 US disclosed
EP-0786493-A1 Rubber composition based on a diene polymer having a silanol group and containing a derivative of an organosilane COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN-MICHELIN & CIE (FR) 1997-07-30 EP disclosed
US-5622784-A WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM SEIKO EPSON CORPORATION (JP) 1997-04-22 US disclosed
EP-0767206-A1 Rubber composition based on a diene polymer containing moieties from organosilane compounds for use in tire treads COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN-MICHELIN & CIE (FR) 1997-04-09 EP disclosed
EP-0417755-B1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO LTD (JP) 1993-12-29 EP disclosed
US-5103000-A PACKING FOR CHROMATOGRAPHY AND METHOD FOR SEPARATING WATER SOLUBLE ORGANIC COMPOUNDS USING THE SAME DAISO CO., LTD. (JP) 1992-04-07 US disclosed
EP-0417755-A1 Packing for chromatography and its use for separating water soluble organic compounds DAISO CO., LTD. (JP) 1991-03-20 EP disclosed