Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 5/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6148647 | 1.00 | PDCD1 (0.45) | PDCD1CD274MRGPRX4TP53HTT | |
| SCHEMBL5079663 | 0.91 | PDCD1 (0.47) | PDCD1CD274MRGPRX4TP53HTT | |
| SCHEMBL6148645 | 0.91 | PDCD1 (0.47) | PDCD1CD274MRGPRX4TP53HTT | |
| SCHEMBL6149436 | 0.87 | MRGPRX4 (0.42) | PDCD1CD274MRGPRX4TP53HTT | |
| SCHEMBL6149441 | 0.87 | MRGPRX4 (0.42) | PDCD1CD274MRGPRX4TP53HTT | |
| SCHEMBL5074588 | 0.85 | TP53 (0.37) | MRGPRX4TP53HTTPDE4B | |
| SCHEMBL5074596 | 0.85 | TP53 (0.37) | MRGPRX4TP53HTTPDE4B | |
| SCHEMBL5079669 | 0.83 | PDCD1 (0.49) | PDCD1CD274MRGPRX4TP53HTT | |
| SCHEMBL5079666 | 0.82 | PDCD1 (0.49) | PDCD1CD274MRGPRX4TP53HTT | |
| SCHEMBL6150443 | 0.82 | PDCD1 (0.49) | PDCD1CD274MRGPRX4TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |