Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6149436 | 1.00 | MRGPRX4 (0.42) | MRGPRX4TP53HTTS1PR1S1PR5 | |
| SCHEMBL5075834 | 0.92 | MRGPRX4 (0.39) | MRGPRX4TP53HTTPDCD1CD274 | |
| SCHEMBL6149439 | 0.91 | MRGPRX4 (0.44) | MRGPRX4TP53HTTS1PR1S1PR5 | |
| SCHEMBL6148647 | 0.87 | PDCD1 (0.45) | MRGPRX4TP53HTTPDCD1CD274 | |
| SCHEMBL6148643 | 0.87 | PDCD1 (0.45) | MRGPRX4TP53HTTPDCD1CD274 | |
| SCHEMBL5077199 | 0.87 | TP53 (0.35) | MRGPRX4TP53HTTS1PR1S1PR5 | |
| SCHEMBL5077196 | 0.87 | TP53 (0.35) | MRGPRX4TP53HTTS1PR1S1PR5 | |
| SCHEMBL5075839 | 0.84 | MRGPRX4 (0.43) | MRGPRX4TP53HTTS1PR1S1PR5 | |
| SCHEMBL5075838 | 0.83 | MRGPRX4 (0.44) | MRGPRX4TP53HTTS1PR1S1PR5 | |
| SCHEMBL6151025 | 0.83 | HIF1A (0.43) | MRGPRX4TP53HTTS1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |