Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 8/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | PRKX | P51817 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6148746 | 1.00 | HIF1A (0.57) | HIF1AHRH3ALDH1A1NPC1POLB | |
| SCHEMBL5079633 | 0.92 | HIF1A (0.48) | HIF1AHRH3ALDH1A1NPC1POLB | |
| SCHEMBL5079630 | 0.91 | HIF1A (0.69) | HIF1AALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL5080353 | 0.90 | HIF1A (0.57) | HIF1AALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL5080357 | 0.90 | HIF1A (0.57) | HIF1AALDH1A1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL5136664 | 0.89 | HIF1A (0.54) | HIF1AALDH1A1NPC1RAB9A | |
| SCHEMBL5136660 | 0.89 | HIF1A (0.54) | HIF1AALDH1A1NPC1RAB9A | |
| SCHEMBL5079377 | 0.87 | HIF1A (0.53) | HIF1AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5079388 | 0.87 | HIF1A (0.53) | HIF1AALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL5077138 | 0.86 | HIF1A (0.76) | HIF1AALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |