SCHEMBL5077138

SCHEMBL5077138

CO/N=C(/C(=O)OC)c1ccccc1COc1cc(Cl)c(OCc2ccccc2)c(Cl)c1

nearest known ligand 0.76

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.76
LMNA P02545 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ADCYAP1R1 P41586 1/20 0.40
HPGD P15428 1/20 0.40
S1PR1 P21453 1/20 0.39
PRKX P51817 1/20 0.39
ACVR1 Q04771 1/20 0.39
S1PR5 Q9H228 1/20 0.39
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5079630 0.93 HIF1A (0.69) HIF1AALDH1A1SMN1; SMN2KDM4E
SCHEMBL5079512 0.90 HIF1A (0.61) HIF1ALMNAALDH1A1MEN1KMT2A
SCHEMBL5079524 0.90 HIF1A (0.61) HIF1ALMNAALDH1A1MEN1KMT2A
SCHEMBL5075935 0.86 HIF1A (0.60) HIF1AALDH1A1NPC1RAB9A
SCHEMBL6148746 0.86 HIF1A (0.57) HIF1AALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL6148743 0.86 HIF1A (0.57) HIF1AALDH1A1NPC1RAB9ASMN1; SMN2
SCHEMBL5079408 0.86 HIF1A (0.60) HIF1ALMNAALDH1A1MEN1KMT2A
SCHEMBL6150462 0.85 HIF1A (0.59) HIF1ALMNAALDH1A1MEN1KMT2A
SCHEMBL5074684 0.85 HIF1A (0.59) HIF1ALMNAALDH1A1MEN1KMT2A
SCHEMBL5076404 0.84 HIF1A (0.58) HIF1ALMNAALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HIF1A 4554/4885LMNA 4661/4885ALDH1A1 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.