Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6149503 | 1.00 | MRGPRX4 (0.41) | MRGPRX4THRBOPRL1PPARDPPARA | |
| SCHEMBL5080367 | 0.92 | HIF1A (0.43) | MRGPRX4THRBOPRL1PPARDPPARA | |
| SCHEMBL6149567 | 0.89 | LIPE (0.41) | MRGPRX4 | |
| SCHEMBL6149563 | 0.89 | LIPE (0.41) | MRGPRX4 | |
| SCHEMBL5077012 | 0.87 | MRGPRX4 (0.38) | MRGPRX4HIF1A | |
| SCHEMBL5077003 | 0.87 | MRGPRX4 (0.38) | MRGPRX4HIF1A | |
| SCHEMBL5079624 | 0.85 | MRGPRX4 (0.39) | MRGPRX4HIF1AFFAR1FFAR4 | |
| SCHEMBL5079611 | 0.85 | MRGPRX4 (0.39) | MRGPRX4HIF1AFFAR1FFAR4 | |
| SCHEMBL6151189 | 0.85 | PTGER4 (0.38) | THRBFFAR1CYP11B1CYP11B2THRA | |
| SCHEMBL6151185 | 0.85 | PTGER4 (0.38) | THRBFFAR1CYP11B1CYP11B2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |