SCHEMBL6150091

SCHEMBL6150091

N=C(N)NCCCC[C@H](NC=O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 9/20 0.38
▸ ALOX15 P16050 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ NOD1 Q9Y239 2/20 0.34
▸ NPY4R P50391 4/20 0.34
▸ NPY1R P25929 3/20 0.34
▸ NPY2R P49146 2/20 0.34
▸ NPY5R Q15761 2/20 0.34
▸ DDAH1 O94760 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17553002 0.95 DDAH1 (0.37) FOLH1ALOX15SMN1; SMN2MEN1CYP1A2
SCHEMBL27494369 0.95 DDAH1 (0.37) FOLH1ALOX15SMN1; SMN2MEN1CYP1A2
SCHEMBL24135883 0.87 C3AR1 (0.41) FOLH1SMN1; SMN2NOD1DDAH1
SCHEMBL12210960 0.84 NPY4R (0.39) ALOX15SMN1; SMN2MEN1CYP1A2KMT2A
SCHEMBL20999856 0.84 EPHX1 (0.36) FOLH1ALOX15SMN1; SMN2MEN1CYP1A2
SCHEMBL20999364 0.82 EPHX1 (0.38) ALOX15SMN1; SMN2MEN1CYP1A2KMT2A
SCHEMBL20999352 0.82 EPHX1 (0.38) ALOX15SMN1; SMN2MEN1CYP1A2KMT2A
SCHEMBL8663718 0.82 GNPAT (0.45) FOLH1ALOX15SMN1; SMN2MEN1CYP1A2
SCHEMBL8662167 0.82 GNPAT (0.45) FOLH1ALOX15SMN1; SMN2MEN1CYP1A2
SCHEMBL27532875 0.82 FOLH1 (0.41) FOLH1ALOX15SMN1; SMN2MEN1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0477295-B2 PLATELET AGGREGATION INHIBITORS MILLENNIUM PHARM INC (US) 2005-11-16 — — EP disclosed
US-5968902-A POLYPEPTIDES FOR ANTIISCHEMIC AGENTS FOR PLATELET DISORDERS COR THERAPEUTICS, INC. (US) 1999-10-19 — — US disclosed
US-5935926-A Platelet aggregation inhibitors COR THERAPEUTICS, INC. (US) 1999-08-10 — — US disclosed
US-5843897-A Platelet aggregation inhibitors COR THERAPEUTICS, INC. (US) 1998-12-01 — — US disclosed
EP-0639202-B1 STABLE POLYPEPTIDE COMPOSITION COR THERAPEUTICS INC (US) 1998-11-25 — — EP disclosed
US-5807825-A ADMINISTERING A CYCLIC PEPTIDE TO TREAT OR PREVENT A PLATELET ASSOCIATED ISCHEMIC DISORDER COR THERAPEUTICS, INC. (US) 1998-09-15 — — US disclosed
US-5786333-A Platelet aggregation inhibitors COR THERAPEUTICS, INC. (US) 1998-07-28 — — US disclosed
US-5770564-A ADMINISTERING CYCLIC HEXAPEPTIDE TO TREAT CARDIOVASCULAR DISORDERS COR THERAPEUTICS, INC. (US) 1998-06-23 — — US disclosed
US-5759999-A TREATING CARDIOVASCULAR DISORDER BY ADMINISTERING A CYCLIC PEPTIDE EXTRACTS FROM SNAKE VENOMS COR THERAPEUTICS, INC. (US) 1998-06-02 — — US disclosed
US-5756451-A ANTIISCHEMIC AGENTS COR THERAPEUTICS, INC. (US) 1998-05-26 — — US disclosed
US-5686570-A Cyclic heptapeptide Eptifibatide claimed; antithrombotic; fibrinogen receptor antagonists COR THERAPEUTICS, INC. (US) 1997-11-11 — — US disclosed
US-5686571-A OLIGOPEPTIDES, SNAKE VENOM COR THERAPEUTICS, INC. (US) 1997-11-11 — — US disclosed
US-5686569-A OLIGOPEPTIDES, SNAKE VENOM COR THERAPEUTICS, INC. (US) 1997-11-11 — — US disclosed
EP-0751219-A1 Platelet aggregation inhibitors COR THERAPEUTICS, INC. (US) 1997-01-02 — — EP disclosed
EP-0477295-B1 PLATELET AGGREGATION INHIBITORS COR THERAPEUTICS INC (US) 1997-01-02 — — EP disclosed
EP-0639202-A1 STABLE POLYPEPTIDE COMPOSITION COR THERAPEUTICS, INC. (US) 1995-02-22 — — EP disclosed
WO-1993022335-A1 STABLE POLYPEPTIDE COMPOSITION COR THERAPEUTICS, INC. (US) 1993-11-11 — — WO disclosed
EP-0477295-A4 PLATELET AGGREGATION INHIBITORS — 1992-10-07 — — EP disclosed
EP-0477295-A1 PLATELET AGGREGATION INHIBITORS. COR THERAPEUTICS INC (US) 1992-04-01 — — EP disclosed
WO-1990015620-A1 PLATELET AGGREGATION INHIBITORS COR THERAPEUTICS, INC. (US) 1990-12-27 — — WO disclosed
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