Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.48 |
| ▸ | PPARG | P37231 | 11/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150597 | 0.91 | PPARA (0.47) | PPARAPPARGHPGDGRB2MEN1 | |
| SCHEMBL6150925 | 0.89 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL5360686 | 0.87 | PPARA (0.47) | PPARAPPARGHPGDMEN1KMT2A | |
| SCHEMBL5360692 | 0.87 | PPARA (0.47) | PPARAPPARGHPGDMEN1KMT2A | |
| SCHEMBL6150631 | 0.86 | PPARA (0.47) | PPARAPPARGHPGDMEN1KMT2A | |
| SCHEMBL6150806 | 0.84 | PPARA (0.46) | PPARAPPARGPPARD | |
| SCHEMBL6661862 | 0.83 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL6658842 | 0.83 | PPARA (0.47) | PPARAPPARGKMT2APPARD | |
| SCHEMBL5360663 | 0.82 | PPARA (0.44) | PPARAPPARGMEN1KMT2APPARD | |
| SCHEMBL6149805 | 0.82 | HPGD (0.51) | PPARAPPARGHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | claimed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | claimed |
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |