SCHEMBL6658842

SCHEMBL6658842

CCO[C@@H](Cc1ccc(OC(C)CC(=O)NCCc2ccccc2F)cc1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.47
PPARG P37231 14/20 0.47
PPARD Q03181 7/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6150313 0.90 KMT2A (0.49) PPARAPPARGPPARDKMT2A
SCHEMBL6150925 0.90 PPARA (0.47) PPARAPPARGPPARD
SCHEMBL6660674 0.89 PPARA (0.48) PPARAPPARGPPARD
SCHEMBL5361717 0.87 PPARA (0.48) PPARAPPARGPPARDKMT2A
SCHEMBL5361713 0.87 PPARA (0.48) PPARAPPARGPPARDKMT2A
SCHEMBL6661862 0.85 PPARA (0.51) PPARAPPARGPPARD
SCHEMBL6150806 0.83 PPARA (0.46) PPARAPPARGPPARD
SCHEMBL5360663 0.83 PPARA (0.44) PPARAPPARGPPARDKMT2A
SCHEMBL6150329 0.83 PPARA (0.48) PPARAPPARGPPARDKMT2A
SCHEMBL6150631 0.81 PPARA (0.47) PPARAPPARGPPARDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004000789-A9 AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS LILLY CO ELI (US) 2004-03-11 WO claimed
WO-2004000789-A9 AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS LILLY CO ELI (US) 2004-03-11 WO disclosed