SCHEMBL6150397

SCHEMBL6150397

CO/N=C(/C(=O)O)c1ccccc1COc1cc(Cl)c(OCC#N)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.50
HTT P42858 2/20 0.39
POLB P06746 1/20 0.39
ALOX15 P16050 1/20 0.39
NR4A2 P43354 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
TP53 P04637 1/20 0.38
MRGPRX4 Q96LA9 3/20 0.38
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6150401 1.00 HIF1A (0.50) HIF1AHTTPOLBALOX15NR4A2
SCHEMBL5079408 0.92 HIF1A (0.60) HIF1AHTTPOLBALOX15NR4A2
SCHEMBL6155058 0.91 HIF1A (0.49) HIF1AHTTNR4A2NPC1RAB9A
SCHEMBL5079413 0.91 HTT (0.43) HIF1AHTTPOLBALOX15NR4A2
SCHEMBL6155063 0.91 HIF1A (0.49) HIF1AHTTNR4A2NPC1RAB9A
SCHEMBL5080508 0.90 HIF1A (0.48) HIF1AHTTPOLBALOX15NR4A2
SCHEMBL5080500 0.90 HIF1A (0.48) HIF1AHTTPOLBALOX15NR4A2
SCHEMBL5079388 0.89 HIF1A (0.53) HIF1AHTTNR4A2NPC1RAB9A
SCHEMBL5079377 0.89 HIF1A (0.53) HIF1AHTTNR4A2NPC1RAB9A
SCHEMBL5136664 0.88 HIF1A (0.54) HIF1AHTTNR4A2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed