Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 6/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150443 | 1.00 | PDCD1 (0.49) | PDCD1CD274HIF1AMRGPRX4TP53 | |
| SCHEMBL5075861 | 0.91 | HIF1A (0.55) | PDCD1CD274HIF1AMRGPRX4TP53 | |
| SCHEMBL5075864 | 0.91 | PDCD1 (0.49) | PDCD1CD274MRGPRX4TP53HTT | |
| SCHEMBL5080568 | 0.89 | PDCD1 (0.47) | PDCD1CD274HIF1AMRGPRX4TP53 | |
| SCHEMBL5080558 | 0.89 | PDCD1 (0.47) | PDCD1CD274HIF1AMRGPRX4TP53 | |
| SCHEMBL6151029 | 0.87 | HIF1A (0.43) | PDCD1CD274HIF1AMRGPRX4TP53 | |
| SCHEMBL6151025 | 0.87 | HIF1A (0.43) | PDCD1CD274HIF1AMRGPRX4TP53 | |
| SCHEMBL5074622 | 0.85 | HIF1A (0.48) | PDCD1CD274HIF1AMRGPRX4TP53 | |
| SCHEMBL5074618 | 0.85 | HIF1A (0.48) | PDCD1CD274HIF1AMRGPRX4TP53 | |
| SCHEMBL5079669 | 0.83 | PDCD1 (0.49) | PDCD1CD274MRGPRX4TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1494991-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | Isagro Ricerca S.r.l. (IT) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003087032-A1 | ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES | ISAGRO RICERCA S.R.L. (IT) | 2003-10-23 | — | — | WO | disclosed |