SCHEMBL6150462

SCHEMBL6150462

CON=C(C(=O)OC)c1ccccc1COc1cc(Cl)c(OCC=C(Cl)Cl)c(Cl)c1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.59
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 2/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 2/20 0.34
MRGPRX4 Q96LA9 2/20 0.34
POLB P06746 1/20 0.34
MAPK1 P28482 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ABL1 P00519 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
RIN1 Q13671 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5074684 1.00 HIF1A (0.59) HIF1AMEN1KMT2AHTTTP53
SCHEMBL5076404 0.91 HIF1A (0.58) HIF1AMEN1KMT2AHTTTP53
SCHEMBL5080518 0.91 HIF1A (0.58) HIF1AMEN1KMT2AHTTTP53
SCHEMBL5074532 0.91 HIF1A (0.48) HIF1AMEN1KMT2AHTTTP53
SCHEMBL5074534 0.91 HIF1A (0.48) HIF1AMEN1KMT2AHTTTP53
SCHEMBL5074585 0.91 HIF1A (0.48) HIF1AMEN1KMT2AHTTTP53
SCHEMBL5074580 0.91 HIF1A (0.48) HIF1AMEN1KMT2AHTTTP53
SCHEMBL5080515 0.90 HIF1A (0.57) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL5080502 0.88 HIF1A (0.55) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL5077035 0.87 HIF1A (0.54) HIF1AMEN1KMT2AHTTTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP claimed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO claimed