SCHEMBL5076404

SCHEMBL5076404

CO/N=C(/C(=O)OC)c1ccccc1COc1cc(Cl)c(OCC=C(Br)Br)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.58
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
MAPT P10636 2/20 0.33
MRGPRX4 Q96LA9 2/20 0.33
TP53 P04637 1/20 0.33
HTT P42858 1/20 0.33
POLB P06746 1/20 0.33
MAPK1 P28482 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ABL1 P00519 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
RIN1 Q13671 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5074684 0.91 HIF1A (0.59) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL6150854 0.91 HIF1A (0.48) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL6150853 0.91 HIF1A (0.48) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL6150462 0.91 HIF1A (0.59) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL5080518 0.91 HIF1A (0.58) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL5074612 0.91 HIF1A (0.46) HIF1AMEN1KMT2AMRGPRX4TP53
SCHEMBL5077035 0.90 HIF1A (0.54) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL5080502 0.87 HIF1A (0.55) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL5080515 0.87 HIF1A (0.57) HIF1AMEN1KMT2AMAPTMRGPRX4
SCHEMBL5077138 0.84 HIF1A (0.76) HIF1AMEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HIF1A 4554/4885MEN1 2918/4885KMT2A 3499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.