Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.55 |
| ▸ | PPARG | P37231 | 16/20 | 0.48 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501937 | 0.90 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL5361731 | 0.83 | TSHR (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3963793 | 0.83 | TSHR (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3963046 | 0.83 | TSHR (0.54) | PPARAPPARGPPARD | |
| SCHEMBL5353330 | 0.83 | TSHR (0.54) | PPARAPPARGPPARD | |
| SCHEMBL5721743 | 0.82 | TSHR (0.55) | PPARAPPARGPPARD | |
| SCHEMBL5357008 | 0.79 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL14501920 | 0.79 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL6156216 | 0.79 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL5373003 | 0.79 | PPARA (0.52) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |