Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL6151558 | 1.00 | DNM1 (0.46) | DNM1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL8146923 | 0.93 | DNM1 (0.48) | DNM1CA12CA1CA2CA9 | |
| Bromide SCHEMBL6151303 | 0.90 | DNM1 (0.50) | DNM1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL6150730 | 0.90 | DNM1 (0.50) | DNM1CA12CA1CA2CA9 | |
| Bromide SCHEMBL6150481 | 0.90 | DNM1 (0.50) | DNM1CA12CA1CA2CA9 | |
| Iodide SCHEMBL6151440 | 0.88 | DNM1 (0.44) | DNM1CA12CA1CA2CA9 | |
| Iodide SCHEMBL6151762 | 0.84 | CA12 (0.39) | DNM1CA12CA1CA2CA9 | |
| Iodide SCHEMBL6151012 | 0.84 | CA1 (0.32) | CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL1357923 | 0.83 | DNM1 (0.44) | DNM1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL3587494 | 0.83 | DNM1 (0.44) | DNM1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0944564-B9 | HALOGEN EXCHANGE REACTIONS AND USES THEREOF | ALBEMARLE CORP (US) | 2005-01-19 | — | — | EP | disclosed |
| US-6455718-B1 | FOR CONTINUOUSLY RECOVERING CHLOROPENTAFLUOROBENZENE OR BROMOPENTAFLUOROBENZENE FROM VAPOR PHASE | ALBEMARLE CORPORATION | 2002-09-24 | — | — | US | disclosed |
| EP-0944564-B1 | HALOGEN EXCHANGE REACTIONS AND USES THEREOF | ALBEMARLE CORP (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6241917-B1 | Halogen exchange reactions in preparing catalysts and their precursors | ALBEMARLE CORPORATION | 2001-06-05 | — | — | US | disclosed |
| US-5965781-A | PURIFYING THE CATALYST FOR IMPROVED PERFORMANCE BY DISSOLVING THE PHOSPHONIUM HALIDE IN A LIQUID CYCLIC ETHER, REMOVING THE SOLID IMPURITIES, ADDING A NONSOLVENT TO PRECIPITATE; REACTING AN ALKALI FLUORIDE AND HALO(S)BENZENE | ALBEMARLE CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5824827-A | Halogen exchange reactions | ALBEMARLE CORPORATION (US) | 1998-10-20 | — | — | US | disclosed |
| US-5789631-A | Production of perhalobenzenes | ALBEMARLE CORPORATION (US) | 1998-08-04 | — | — | US | disclosed |