Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6410951 | 0.99 | GAA (0.54) | GAARAD52KCNH2MAPTMAPK1 | |
| SCHEMBL5707930 | 0.93 | GAA (0.58) | GAARAD52KCNH2MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5707956 | 0.92 | GAA (0.56) | GAARAD52KCNH2MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5707958 | 0.88 | GAA (0.52) | GAARAD52KCNH2MAPTMAPK1 | |
| SCHEMBL6151485 | 0.84 | MAPT (0.50) | GAARAD52KCNH2MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL6413349 | 0.83 | MAPT (0.49) | GAARAD52KCNH2MAPTMAPK1 | |
| SCHEMBL5203962 | 0.79 | GAA (0.65) | GAARAD52KCNH2MAPTMAPK1 | |
| SCHEMBL2137477 | 0.78 | GAA (0.39) | GAARAD52MAPTMAPK1HTT | |
| Hydrochloric Acid SCHEMBL2535075 | 0.78 | GAA (0.38) | GAARAD52MAPTMAPK1HTT | |
| SCHEMBL6151838 | 0.77 | GAA (0.67) | GAARAD52KCNH2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1518860-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogene atoms by a 4-aminophenyle group for dyeing keratinic fibres | L'OREAL (FR) | 2005-03-30 | — | — | EP | claimed |