Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | RAD52 | P43351 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5707956 | 0.99 | GAA (0.56) | GAARAD52MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL5707958 | 0.94 | GAA (0.52) | GAARAD52MAPTKDM4EMAPK1 | |
| SCHEMBL6151173 | 0.93 | GAA (0.55) | GAARAD52MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL6410951 | 0.92 | GAA (0.54) | GAARAD52MAPTKDM4EMAPK1 | |
| SCHEMBL5707933 | 0.83 | MAPT (0.53) | GAARAD52MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL5707970 | 0.82 | MAPT (0.51) | GAARAD52MAPTKDM4EMAPK1 | |
| SCHEMBL6152146 | 0.79 | GAA (0.47) | GAARAD52MAPTKDM4EHTT | |
| SCHEMBL5707960 | 0.79 | GAA (0.47) | GAARAD52MAPTKDM4EHTT | |
| SCHEMBL5707917 | 0.79 | MAPT (0.48) | GAARAD52MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL5707967 | 0.78 | GAA (0.46) | GAARAD52MAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1462445-B1 | Paraphenyldiamine derivatives concisting of a cyclic diaza group substituted by a cationic radical and use of these derivatives for dyeing keratin fibres | OREAL (FR) | 2006-10-18 | — | — | EP | claimed |
| EP-1462445-B1 | Paraphenyldiamine derivatives concisting of a cyclic diaza group substituted by a cationic radical and use of these derivatives for dyeing keratin fibres | OREAL (FR) | 2006-10-18 | — | — | EP | disclosed |