Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.58 |
| ▸ | PPARG | P37231 | 10/20 | 0.58 |
| ▸ | PPARD | Q03181 | 5/20 | 0.58 |
| ▸ | LTA4H | P09960 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151261 | 1.00 | PPARA (0.58) | PPARAPPARGPPARDLTA4HPOLB | |
| SCHEMBL3956814 | 0.89 | PPARA (0.61) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL5338861 | 0.87 | PPARA (0.75) | PPARAPPARGPPARDLTA4HLMNA | |
| SCHEMBL4758109 | 0.87 | PPARA (0.75) | PPARAPPARGPPARDLTA4HLMNA | |
| SCHEMBL15811673 | 0.87 | PPARA (0.75) | PPARAPPARGPPARDLTA4HLMNA | |
| SCHEMBL4756258 | 0.86 | PPARA (0.61) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7212899 | 0.86 | PPARA (0.73) | PPARAPPARGPPARDLTA4HLMNA | |
| Hydrochloric Acid SCHEMBL7212895 | 0.86 | PPARA (0.73) | PPARAPPARGPPARDLTA4HLMNA | |
| SCHEMBL4756299 | 0.85 | PPARA (0.63) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL5993658 | 0.85 | PPARA (0.66) | PPARAPPARGPPARDLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |