Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.61 |
| ▸ | PPARG | P37231 | 15/20 | 0.61 |
| ▸ | PPARD | Q03181 | 7/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756299 | 0.94 | PPARA (0.63) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL4758161 | 0.92 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL4755486 | 0.91 | PPARA (0.74) | PPARAPPARGPPARD | |
| SCHEMBL4758109 | 0.89 | PPARA (0.75) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL15811673 | 0.89 | PPARA (0.75) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL5338861 | 0.89 | PPARA (0.75) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7212899 | 0.88 | PPARA (0.73) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7212895 | 0.88 | PPARA (0.73) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL5993658 | 0.87 | PPARA (0.66) | PPARAPPARGPPARDLMNAL3MBTL1 | |
| SCHEMBL6151263 | 0.86 | PPARA (0.58) | PPARAPPARGPPARDLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008010238-A2 | ANTIDIABETIC AZABICYCLO [3. 1. 0] HEXAN COMPOUNDS | LUPIN LIMITED (IN) | 2008-01-24 | — | — | WO | disclosed |