Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.50 |
| ▸ | PPARG | P37231 | 13/20 | 0.50 |
| ▸ | PPARD | Q03181 | 11/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5396376 | 0.86 | PPARA (0.52) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL6148806 | 0.84 | MEN1 (0.61) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5364857 | 0.81 | PPARA (0.65) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL3963061 | 0.80 | MEN1 (0.51) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL3963053 | 0.80 | MEN1 (0.51) | PPARAPPARGPPARDALDH1A1MEN1 | |
| SCHEMBL5024524 | 0.80 | MEN1 (0.52) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5360733 | 0.80 | GAA (0.59) | PPARAPPARGPPARDLMNA | |
| SCHEMBL5027071 | 0.79 | MEN1 (0.51) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5360759 | 0.77 | PPARA (0.49) | PPARAPPARGPPARDMEN1KMT2A | |
| SCHEMBL5364021 | 0.76 | TRPM8 (0.48) | PPARAPPARGPPARDLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |