Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 8/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8643866 | 0.91 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRHIF1AVCAM1 | |
| SCHEMBL15326941 | 0.89 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRHIF1AVCAM1 | |
| SCHEMBL16590368 | 0.89 | ALDH1A1 (0.53) | ALDH1A1TDP1TSHRHIF1AVCAM1 | |
| SCHEMBL7900446 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TDP1TSHRHIF1AVCAM1 | |
| SCHEMBL8318666 | 0.84 | ALDH1A1 (0.63) | ALDH1A1TDP1TSHRVCAM1KDM4E | |
| SCHEMBL29390088 | 0.83 | TDP1 (0.62) | ALDH1A1TDP1TSHRVCAM1KDM4E | |
| SCHEMBL27752508 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRVCAM1KDM4E | |
| SCHEMBL14174537 | 0.83 | ALDH1A1 (0.62) | ALDH1A1TDP1TSHRKDM4ELMNA | |
| SCHEMBL127252 | 0.83 | TDP1 (0.62) | ALDH1A1TDP1TSHRVCAM1KDM4E | |
| SCHEMBL27758417 | 0.82 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRVCAM1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414128-A | Dehydrofluorination for amination | CASSELLA AG (DE) | 1995-05-09 | — | — | US | claimed |
| EP-2809657-B1 | NOVEL THERAPEUTIC AGENTS | EURO CELTIQUE SA (LU) | 2017-09-06 | — | — | EP | disclosed |
| EP-2834215-B1 | PROCESS FOR MAKING BENDAMUSTINE | SYNTHON BV (NL) | 2017-04-26 | — | — | EP | disclosed |
| EP-2834215-B1 | PROCESS FOR MAKING BENDAMUSTINE | SYNTHON BV (NL) | 2017-04-26 | — | — | EP | disclosed |
| US-20150086551-A1 | Novel Therapeutic Agents | CRYSTAL BIOPHARMACEUTICAL LLC | 2015-03-26 | — | — | US | disclosed |
| US-20150086551-A1 | Novel Therapeutic Agents | CRYSTAL BIOPHARMACEUTICAL LLC | 2015-03-26 | — | — | US | disclosed |
| EP-2834215-A1 | PROCESS FOR MAKING BENDAMUSTINE | Synthon BV (NL) | 2015-02-11 | — | — | EP | disclosed |
| WO-2013150020-A1 | PROCESS FOR MAKING BENDAMUSTINE | SYNTHON BV (NL) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013150020-A1 | PROCESS FOR MAKING BENDAMUSTINE | SYNTHON BV (NL) | 2013-10-10 | — | — | WO | disclosed |
| WO-2013113838-A1 | NOVEL THERAPEUTIC AGENTS | EURO-CELTIQUE (LU) | 2013-08-08 | — | — | WO | disclosed |
| EP-0280187-B1 | HAIR DYEING COMPOSITIONS WITH DIRECT-DYEING NITRO-DIPHENYL AMINE DERIVATIVES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-5041143-A | N,N'-disubstituted nitro-para-phenylenediamines, and dyeing compositions containing the same | L'OREAL (FR) | 1991-08-20 | — | — | US | disclosed |
| US-4981486-A | Washfast, lightfast; for bleached or permed hair | L'OREAL (FR) | 1991-01-01 | — | — | US | disclosed |
| US-4981486-A | Washfast, lightfast; for bleached or permed hair | L'OREAL (FR) | 1991-01-01 | — | — | US | disclosed |
| US-4910341-A | Reacting chloroethyl chloroformate with 4-halo-3-nitroaniline in presence of a base; cyclization; alkaline hydrolysis | L'OREAL (FR) | 1990-03-20 | — | — | US | disclosed |
| US-4859206-A | Hair dye preparations containing nitrodiphenylamine derivative | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-08-22 | — | — | US | disclosed |
| EP-0280187-A1 | Hair dyeing compositions with direct-dyeing nitro-diphenyl amine derivatives | Henkel Kommanditgesellschaft auf Aktien (DE) | 1988-08-31 | — | — | EP | disclosed |
| US-4690685-A | HAIR DYES | L'OREAL (FR) | 1987-09-01 | — | — | US | disclosed |
| US-RE30798-E | BY REACTING 4-FLUORO-3-NITROANILINES WITH AMMONIA OR A PRIMARY OR SECONDARY AMINE | CLAIROL INCORPORATED (US) | 1981-11-17 | — | — | US | disclosed |
| US-3944612-A | HAIR DYE INTERMEDIATES | CLAIROL INCORPORATED (US) | 1976-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150086551-A1 | Novel Therapeutic Agents | HDAC1, HDAC11, HDAC5 | ALDH1A1 779/4885TDP1 614/4885TSHR 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.