SCHEMBL6151449

SCHEMBL6151449

N#Cc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.93

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.93
KMT2A Q03164 3/20 0.93
ALDH1A1 P00352 3/20 0.93
MAPK1 P28482 3/20 0.93
MAPT P10636 2/20 0.93
TP53 P04637 1/20 0.93
CYP3A4 P08684 1/20 0.93
HPGD P15428 1/20 0.93
SMN1; SMN2 Q16637 1/20 0.93
KDM4E B2RXH2 1/20 0.36
HTT P42858 2/20 0.33
GLA P06280 1/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
NPY1R P25929 1/20 0.31
NPY2R P49146 1/20 0.31
NSD2 O96028 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorothalonil SCHEMBL8574863 0.96 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL1487631 0.96 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL21254 0.96 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL8200626 0.96 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL1033734 0.96 MEN1 (0.86) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL10855066 0.93 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL4647292 0.93 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL9318007 0.93 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL4395622 0.93 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL7867757 0.93 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 280 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163296-B Preparation method of 1, 3-dichloro-2, 4, 6-trifluorobenzene 阜新睿光氟化学有限公司 2023-10-13 CN claimed
CN-111285783-B Refining and purifying system and method for high-content chlorothalonil 江苏新河农用化工有限公司 2023-04-18 CN claimed
CN-111285784-B Unqualified chlorothalonil purification system and method 江苏新河农用化工有限公司 2023-04-18 CN claimed
CN-115025672-A Pentachlorobenzonitrile continuous production equipment capable of automatically proportioning and processing method thereof 江苏维尤纳特精细化工有限公司 2022-09-09 CN claimed
CN-114957276-A Active ester curing agent and preparation method thereof, epoxy resin composition, composite film and application thereof 深圳先进电子材料国际创新研究院 2022-08-30 CN claimed
CN-114805125-A Synthetic method of fluorine-containing cyanophenyl compound 石家庄圣泰化工有限公司 2022-07-29 CN claimed
CN-112608220-B Synthetic method of 3, 5-difluorophenol 浙江中欣氟材股份有限公司 2022-06-07 CN claimed
CN-112457197-B Preparation method of compound 2, 4, 6-trifluorobenzylamine 浙江丽晶化学有限公司 2022-05-13 CN claimed
CN-114163296-A Preparation method of 1, 3-dichloro-2, 4, 6-trifluorobenzene 阜新睿光氟化学有限公司 2022-03-11 CN claimed
CN-114002350-A Method for detecting content of organic impurities in tetrachlorodicyanobenzene 江苏新河农用化工有限公司 2022-02-01 CN claimed
US-20020035301-A1 Method for production of aromatic fluorine compound NIPPON SHOKUBAI CO., LTD. (JP) 2002-03-21 US claimed
CN-1273238-A Fixed-bed process for preparing pentachlorophenyl nitrile by catalytic chloration of phenyl nitrile NANTIAN INDUSTRY CO LTD HUNAN (CN) 2000-11-15 CN claimed
EP-0899256-A2 Method for production of organic fluorine compound NIPPON SHOKUBAI CO., LTD. (JP) 1999-03-03 EP claimed
EP-0497213-B1 Process for producing 3,5-difluoroaniline ISHIHARA SANGYO KAISHA (JP) 1995-09-27 EP claimed
EP-0497213-A2 Process for producing 3,5-difluoroaniline ISHIHARA SANGYO KAISHA, LTD. (JP) 1992-08-05 EP claimed
US-4957722-A CHLORINATION OF METAL OXIDES, COKE, CHAR ALUMINUM COMPANY OF AMERICA (US) 1990-09-18 US claimed
US-4684734-A Method for manufacture or organic fluorine compounds NIPPON SHOKUBAI KK CO., LTD. (JP) 1987-08-04 US claimed
US-4459274-A ALUMINOUS MATERIALS, METAL AND METALLOID OXIDES, COKE ATLANTIC RICHFIELD COMPANY (US) 1984-07-10 US claimed
US-3984487-A HEATING PENTACHLOROBENZONITRILE IN SULFURIC ACID AND A NITRATING AGENT TEXACO DEVELOPMENT CORPORATION (US) 1976-10-05 US claimed
US-3959370-A HERBICIDE JEFFERSON CHEMICAL COMPANY, INC. (US) 1976-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035301-A1 Method for production of aromatic fluorine compound AFF4, AFF2, AFF1 MEN1 2142/4885KMT2A 1093/4885ALDH1A1 4338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.