SCHEMBL1033734

SCHEMBL1033734

N#Cc1c(Cl)c(Cl)c(C#N)c(Cl)c1Cl

nearest known ligand 0.86

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.86
KMT2A Q03164 3/20 0.86
ALDH1A1 P00352 3/20 0.86
MAPK1 P28482 3/20 0.86
MAPT P10636 2/20 0.86
TP53 P04637 1/20 0.86
CYP3A4 P08684 1/20 0.86
HPGD P15428 1/20 0.86
SMN1; SMN2 Q16637 1/20 0.86
KDM4E B2RXH2 2/20 0.37
HTT P42858 2/20 0.34
GLA P06280 1/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
NPY1R P25929 1/20 0.32
NPY2R P49146 1/20 0.32
NSD2 O96028 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151449 0.96 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL18388942 0.93 MEN1 (0.87) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL8574863 0.93 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL1487631 0.93 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL8200626 0.93 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL21254 0.93 MEN1 (1.00) MEN1KMT2AALDH1A1MAPK1MAPT
SCHEMBL11322706 0.92 MEN1 (0.86) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL4395622 0.89 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL10855066 0.89 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT
Chlorothalonil SCHEMBL9318007 0.89 MEN1 (0.93) MEN1KMT2AALDH1A1MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727911-A2 FLUORINATION METHODS, REAGENTS, FLUORINATED COMPOSITIONS, AND METHODS OF MANUFACTURE FLUOROK LIMITED (GB) 2026-04-22 EP claimed
EP-4569559-A1 GLASSY ORGANIC FRAMEWORK ION-CONDUCTIVE MEMBRANES Wisconsin Alumni Research Foundation (US) 2025-06-18 EP claimed
CN-120136732-A Method for purifying tetrachloro terephthalonitrile 江苏新河农用化工有限公司 2025-06-13 CN claimed
CN-120058508-A Preparation method of 2,4, 5-trifluoro-phenylacetic acid 浙江昌海制药有限公司 2025-05-30 CN claimed
CN-120026490-A Porous polyethylene/carbon black composite electrode material and preparation method and application thereof 浙江理工大学 2025-05-23 CN claimed
CN-120016085-A Solid electrolyte fiber diaphragm and preparation method and application thereof 中国石油化工股份有限公司 2025-05-16 CN claimed
CN-119856312-A Glass-like organic framework ion-conducting separator 威斯康星州男校友研究基金会 2025-04-18 CN claimed
CN-119823381-A Porous organic polymer containing thianthrene ring, and preparation method and application thereof 中国科学院兰州化学物理研究所 2025-04-15 CN claimed
CN-119390975-A Dispersible covalent triazine skeleton and preparation method and application thereof 人工智能与数字经济广东省实验室(深圳) 2025-02-07 CN claimed
CN-119320133-A Halogen modified ultramicropore carbon material, preparation method and application thereof 中国平煤神马控股集团有限公司 2025-01-17 CN claimed
US-6452046-B2 HEATING 2,3,5,6-TETRACHLORO-1,4-BENZENEDIAMIDE SDS BIOTECH K.K. (JP) 2002-09-17 US claimed
WO-2002034706-A1 PREPARATION OF 4-METHYL-2, 3, 5, 6-TETRAFLUOROBENZYL ALCOHOL SYNGENTA LIMITED (GB) 2002-05-02 WO claimed
US-20010025121-A1 Process for producing 2, 3, 5, 6-tetrachloro-1, 4-benzenedicarboxylic acid SDS BIOTECH K.K. 2001-09-27 US claimed
EP-0594317-B1 Cyanoacrylate adhesives with improved cured thermal properties utilizing substituted aromatic additive LOCTITE CORP (US) 1997-09-03 EP claimed
EP-0390394-B1 Composition and use ZENECA LTD (GB) 1994-06-15 EP claimed
US-5125967-A For water supply systems, paints, coatings IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-30 US claimed
EP-0390394-A2 Composition and use ZENECA LIMITED (GB) 1990-10-03 EP claimed
US-4684734-A Method for manufacture or organic fluorine compounds NIPPON SHOKUBAI KK CO., LTD. (JP) 1987-08-04 US claimed
US-4556426-A HALOGENATED AROMATIC DINITRILES TILE COUNCIL OF AMERICA, INC. (US) 1985-12-03 US claimed
US-3975424-A FROM TETRACHLOROPHTHALONITRILE AND POTASSIUM FLUORIDE AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JA) 1976-08-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010025121-A1 Process for producing 2, 3, 5, 6-tetrachloro-1, 4-benzenedicarboxylic acid HAO2, HAAO, HAO1 MEN1 4443/4885KMT2A 1081/4885ALDH1A1 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.