Bromide

Bromide

SCHEMBL6151479

CCCCN(CCCC)[P+](N(CCCC)CCCC)(N(CCCC)CCCC)N(CCCC)CCCC.[Br-]

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.39
CA1 P00915 4/20 0.39
CA9 Q16790 4/20 0.39
ALDH1A1 P00352 2/20 0.39
ALDH2 P05091 1/20 0.39
CA2 P00918 2/20 0.36
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP8 P22894 1/20 0.36
TSHR P16473 4/20 0.35
LMNA P02545 1/20 0.35
DNM1 Q05193 4/20 0.35
THRB P10828 1/20 0.33
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
ALOX12 P18054 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL6151762 0.94 CA12 (0.39) CA12CA1CA9ALDH1A1ALDH2
Hydrochloric Acid SCHEMBL3592047 0.94 CA12 (0.39) CA12CA1CA9ALDH1A1ALDH2
Bromide SCHEMBL6731553 0.92 CA12 (0.37) CA12CA1CA9ALDH1A1ALDH2
Bromide SCHEMBL6151303 0.88 DNM1 (0.50) CA12CA1CA9ALDH1A1CA2
Bromide SCHEMBL6150481 0.88 DNM1 (0.50) CA12CA1CA9ALDH1A1CA2
Iodide SCHEMBL4346703 0.86 CA12 (0.37) CA12CA1CA9ALDH1A1ALDH2
Bromide SCHEMBL7669293 0.86 DNM1 (0.36) CA12CA1CA9ALDH1A1ALDH2
Iodide SCHEMBL6151091 0.86 CA12 (0.37) CA12CA1CA9ALDH1A1ALDH2
Bromide SCHEMBL7929786 0.86 CA12 (0.32) CA12CA1CA9ALDH1A1ALDH2
Bromide SCHEMBL7929788 0.84 DNM1 (0.33) CA12CA1CA9CA2DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115216010-A Method for rapidly preparing polysulfone resin 中国科学院长春应用化学研究所 2022-10-21 CN disclosed
EP-0944564-B9 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORP (US) 2005-01-19 EP disclosed
EP-1054853-B1 CATALYST RECOVERY FOR HALOGEN EXCHANGE REACTIONS ALBEMARLE CORP (US) 2003-03-19 EP disclosed
EP-1015402-B1 Method for producing compounds containing fluorine, in particular fluorobenzaldehydes and fluorobenzonitriles CLARIANT GMBH (DE) 2002-12-04 EP disclosed
US-6455718-B1 FOR CONTINUOUSLY RECOVERING CHLOROPENTAFLUOROBENZENE OR BROMOPENTAFLUOROBENZENE FROM VAPOR PHASE ALBEMARLE CORPORATION 2002-09-24 US disclosed
EP-0944564-B1 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORP (US) 2002-03-20 EP disclosed
US-6241917-B1 Halogen exchange reactions in preparing catalysts and their precursors ALBEMARLE CORPORATION 2001-06-05 US disclosed
US-6215032-B1 SOLVENT EXTRACTION; SEPARATING AMINOPHOSPHONIUM CATALYST; FLUORINATION OF HALOAROMATIC COMPOUND BY REPLACEMENT REACTION WITH ALKALI METAL FLUORIDE ALBEMARLE CORPORATION 2001-04-10 US disclosed
US-6166242-A Method for producing compounds containing fluorine, in particular fluorobenzaldhydes and fluorobenzonitriles AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) 2000-12-26 US disclosed
EP-1015402-A1 METHOD FOR PRODUCING COMPOUNDS CONTAINING FLUORINE, IN PARTICULAR FLUOROBENZALDHYDES AND FLUOROBENZONITRILES Aventis Research & Technologies GmbH & Co. KG (DE) 2000-07-05 EP disclosed
US-5965781-A PURIFYING THE CATALYST FOR IMPROVED PERFORMANCE BY DISSOLVING THE PHOSPHONIUM HALIDE IN A LIQUID CYCLIC ETHER, REMOVING THE SOLID IMPURITIES, ADDING A NONSOLVENT TO PRECIPITATE; REACTING AN ALKALI FLUORIDE AND HALO(S)BENZENE ALBEMARLE CORPORATION (US) 1999-10-12 US disclosed
WO-1999011588-A1 METHOD FOR PRODUCING COMPOUNDS CONTAINING FLUORINE, IN PARTICULAR FLUOROBENZALDHYDES AND FLUOROBENZONITRILES AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO. KG (DE) 1999-03-11 WO disclosed
US-5824827-A Halogen exchange reactions ALBEMARLE CORPORATION (US) 1998-10-20 US disclosed
US-5789631-A Production of perhalobenzenes ALBEMARLE CORPORATION (US) 1998-08-04 US disclosed